- Basic information
- CohesinDB ID: CDBP00413634
- Locus: chr21-16005991-16006690
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Data sourse: ENCSR000BTU, ENCSR853VWZ, ENCSR193NSH, GSE138405, GSE25021, ENCSR000BLY, GSE101921, ENCSR000ECE, GSE152721, GSE206145-NatGen2015, ENCSR000EDE, GSE112028, GSE126990, GSE108869, ENCSR000ECS, ENCSR000BUC
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Cell type: MCF-7, H1-hESC, Fibroblast, Hela-Kyoto, Ishikawa, A-549, HCAEC, HeLa-S3, SK-N-SH, HeLa-Tet-On, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.878
- Subunit: SMC3,Rad21,SA2,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
42% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 99%,
"5_TxWk": 1%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, RUNX1, PAX8, ONECUT1, CREB1, RAD21, DUX4, OTX2, FOXA1, SMC3, CTCF, SMARCC1, STAG1
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000155313,
- Related loop:
chr21:15875000-15900000~~chr21:16000000-16025000,
chr21:16000000-16025000~~chr21:16175000-16200000,
chr21:16000000-16025000~~chr21:16325000-16350000,
chr21:16000000-16025000~~chr21:16400000-16425000,
chr21:16000000-16025000~~chr21:17250000-17275000,
chr21:16001839-16003762~~chr21:16329724-16331264,
chr21:16001977-16003846~~chr21:16329691-16331745,
chr21:16001998-16003844~~chr21:16329695-16331504,
chr21:16002031-16003807~~chr21:16329708-16331692,
chr21:16002041-16004416~~chr21:16329708-16331761,
chr21:16002066-16003798~~chr21:16329704-16331395,
chr21:16002070-16004771~~chr21:16329660-16331732,
chr21:16002137-16004536~~chr21:16329715-16331630,
chr21:16002506-16003755~~chr21:16329734-16331645,