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Basic information

CohesinDB ID: CDBP00413646

Locus: chr21-16079564-16080614

Data sourse: GSE206145-GSE177045, ENCSR230ZWH, GSE138405, GSE25021, GSE206145, GSE206145-NatGen2015, ENCSR000EDE, GSE126990, GSE108869, ENCSR000ECS, GSE165895

Cell type: MCF-7, RPE, Hela-Kyoto, Fibroblast, HeLa-S3, Liver, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 7% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.922

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 42% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 73%, "5_TxWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, PGR, HMG20A, ZNF660, NME2, PATZ1, FOXA1, HLF, PBX2, RXRB, ATF3, NFIC, ZBTB44, CHD7, IKZF3, MXD4, ZNF189, HDAC3, CDX2, ZNF629, TEAD1, ZNF26, KLF6, ETV1, RCOR2, ESR1, HNF1B, JUN, TCF12, CTCF, BAF155, EP300, SOX5, IRF4, RFX5, E2F1, SMC1, FOXA3, GATAD2A, PDX1, NANOG, CHD8, BRD3, CTBP1, ZSCAN21, ZBTB17, DUX4, ERF, SRF, GATAD1, SAP130, HIC1, ARID3A, TBP, HNF4G, HOXC5, ERG, PAX6, ZNF300, MYC, SMARCA4, TSHZ1, HOMEZ, RAD21, TOP1, RXRA, NKX2-1, GABPA, STAT3, ZNF614, NKX3-1, ZNF639, VDR, NR3C1, CEBPB, ESRRA, CREB1, TBL1XR1, EZH2, KLF8, FEZF1, GRHL2, ZNF664, MIXL1, IRF1, HDAC2, GATA2, ZNF644, ZGPAT, NFIL3, NFYB, ZIM3, MRTFB, ETV5, RUNX1, THAP11, BCL6, SMC1A, CEBPA, NKX2-2, LDB1, SOX13, SMAD3, ZFP37, ZNF654, TBX3, ERG3, SMARCC1, MYBL2, CREBBP, RARA, ZNF384, ZBTB2, RUNX2, GATA4, OSR2, GR, ZNF184, SP3, ARNT, PBX4, DAXX, PRDM9, ZEB2, SMAD4, FOXM1, FOS, CHD1, MED1, CSNK2A1, ZEB1, TEAD3, CEBPD, PIAS1, SMAD1, ZNF3, KLF9, NUP98-HOXA9, MAFK, SP1, BCL11A, HNF4A, REST, ARID1A, ZNF479, ATF7, ZHX1, ASH2L, PHIP, FOXP1, SMC3, STAG1, ZNF394, SKI, FOXA2, CREM, SS18, ZSCAN16, ZNF692, TCF7, HOXB13, BCL3, KDM1A, YY1, RELA, JUNB, BRG1, HIF1A, OTX2, GATA3, TAL1, MAX, TLE3, KLF4, CEBPG, SP7, TP53, PKNOX1, PHOX2B, ELF3, PHF5A, BRD2, NFKBIZ, AR, ARID4B, ZNF366, BRD4, JUND, CUX1, BRCA1, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000155313,

eachgene

Deatailed information for cohesin site CDBP00413646