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Basic information

CohesinDB ID: CDBP00413648

Locus: chr21-16087918-16088278

Data sourse: ENCSR000BLD, ENCSR000BTU, ENCSR000BLY, GSE105028, GSE152721, ENCSR000ECE, GSE206145-NatGen2015, ENCSR000EDE, GSE112028, GSE25021, GSE94872, GSE97394, ENCSR000BUC

Cell type: MCF-7, H1-hESC, Fibroblast, Ishikawa, A-549, HUVEC, HeLa-S3, HUES64, SK-N-SH, HeLa-Tet-On, HAP1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.867

Subunit: Mau2,SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 42% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 90%, "2_TssAFlnk": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, SOX2, FOXA1, NFIC, PAX5, MITF, SFPQ, TEAD1, ETV1, ESR1, USF2, CTCF, TCF12, BAF155, EP300, E2F1, TEAD4, RBPJ, EED, NANOG, CHD8, MYCN, POU5F1, TOP2A, DUX4, ERG, HOXC5, MYC, SMARCA4, RAD21, TOP1, GABPA, STAT3, UBN1, NKX3-1, VDR, NR3C1, CEBPB, CREB1, GATA2, SIX2, ZNF135, RUNX1, ZFX, SMAD3, SMARCC1, ZNF384, RUNX2, GATA4, PBX4, DAXX, ARNT, ATF2, ZNF10, CHD1, CDK8, MED1, CSNK2A1, PIAS1, KLF9, SETDB1, USF1, REST, ARID1A, POU2F3, FOXP1, SMC3, STAG1, FOXA2, SS18, HOXB13, KDM1A, YY1, RELA, NEUROD1, JUNB, ISL1, HIF1A, OTX2, TAL1, MAX, HAND2, TLE3, TCF7L2, TP53, MYOD1, PHOX2B, BRD2, AR, RXR, EGLN2, BRD4, BRCA1, FOSL2

Target gene symbol (double-evidenced CRMs): USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000155313,

eachgene

Deatailed information for cohesin site CDBP00413648