- Basic information
- CohesinDB ID: CDBP00413655
- Locus: chr21-16120717-16121043
-
Data sourse: GSE206145-NatGen2015, GSE67783
-
Cell type: Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
42% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 92%,
"5_TxWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, SMARCA2, SOX2, HNF1A, FOXA1, TFAP4, CHD7, PRDM1, ZNF189, TEAD1, KLF6, ETV1, ESR1, HNF1B, JUN, TCF12, EP300, BAF155, PRDM4, RFX5, E2F1, TEAD4, NANOG, POU5F1, ZNF317, ZBTB48, STAT1, SRF, ERG, HOXC5, MYC, ONECUT1, SMARCA4, ZNF671, TOP1, NKX2-1, STAT3, NKX3-1, VDR, NR3C1, CEBPB, ESRRA, CREB1, GRHL2, IRF1, HDAC2, GATA2, FLI1, ZNF777, ZNF766, MRTFB, NFYB, MAFG, CEBPA, EZH2phosphoT487, SIN3A, SMAD3, SMARCC1, TWIST1, RUNX2, GATA4, PBX4, ARNT, DAXX, NRF1, NFYA, FOXM1, PBX3, CHD1, FOS, MED1, CSNK2A1, ZEB1, CEBPD, PIAS1, KLF9, C11orf30, NUP98-HOXA9, MAFK, NIPBL, SP1, ATF7, POU2F3, CTBP2, FOXP1, PRDM6, STAG2, PPARG, FOXA2, SS18, ZNF692, MAFF, HOXB13, KDM1A, YY1, RELA, JUNB, BRG1, HIF1A, OTX2, GATA3, TAL1, TLE3, KLF4, NR2F2, TP53, ZNF334, MYOD1, ELF3, BRD2, BHLHE40, AR, EGLN2, HSF1, BRD4, JUND, CUX1, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops