- Basic information
- CohesinDB ID: CDBP00413657
- Locus: chr21-16126245-16126854
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Data sourse: GSE138405, GSE62063
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Cell type: Hela-Kyoto, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: NIPBL,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES,Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
42% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 95%,
"5_TxWk": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, SMARCA2, SOX2, XBP1, FOXA1, ATF3, NFIC, ZBTB44, CHD7, TP63, SFPQ, TEAD1, ETV1, ZNF26, KLF6, ESR1, PITX3, USF2, CTCF, TCF12, JUN, BAF155, EP300, RFX5, E2F4, TEAD4, TFAP2C, NANOG, CHD8, ZNF263, POU5F1, MYCN, BRD3, ZBTB17, DUX4, SRF, TBP, ERG, MYC, ONECUT1, SMARCA4, RAD21, LHX2, TOP1, GABPA, STAT3, UBN1, NKX3-1, RCOR1, VDR, NR3C1, CEBPB, ESRRA, ZNF750, CREB1, EBF3, MRTFA, PHF8, ZNF664, EHF, IRF1, GATA2, FLI1, MXI1, MRTFB, CEBPA, EZH2phosphoT487, AFF4, SMAD3, SMARCC1, TWIST1, ZNF384, RUNX2, PBX4, NRF1, FOXM1, PBX3, FOS, CDK8, CHD1, MED1, CSNK2A1, CEBPD, PIAS1, SETDB1, MAFK, BCL11A, SP1, USF1, ARID1A, ZHX1, CTBP2, PHIP, SRSF9, PRDM6, SMC3, ELL2, ZNF394, ZNF283, FOXA2, CHD2, SS18, GTF2B, MAFF, HOXB13, KDM1A, YY1, RELA, JUNB, NEUROD1, BRG1, ISL1, HIF1A, OTX2, GATA3, MAX, GATA1, HAND2, TLE3, KLF4, NR2F2, TCF7L2, KDM5B, TP53, PKNOX1, NFKB1, PHOX2B, ELF3, BRD2, AR, TAF1, ZNF366, BRD4, JUND, BRCA1, FOSL2
- Target gene symbol (double-evidenced CRMs): NRIP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops