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Basic information

CohesinDB ID: CDBP00413666

Locus: chr21-16168229-16170253

Data sourse: GSE206145-GSE177045, GSE138405, GSE126634, GSE152721, GSE62063, GSE206145-NatGen2015, ENCSR000EDE, GSE112028, GSE130135, GSE126990, GSE108869, ENCSR000ECS

Cell type: MCF-7, Hela-Kyoto, Fibroblast, HEK293T, HeLa-S3, HeLa-Tet-On, HAP1, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 4% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.911

Subunit: NIPBL,SA1,Rad21,SA2,Mau2,SMC3

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: False Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 42% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 67%, "7_Enh": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, SMARCA2, ZNF660, ZSCAN5C, SOX2, FOXA1, ZNF362, ZBTB44, PRDM1, IKZF3, KLF14, ZNF189, ZNF629, TEAD1, KLF10, ESR1, HNF1B, CTCF, JUN, TCF12, BAF155, EP300, PRDM4, RFX5, TEAD4, PDX1, EED, NANOG, ZNF425, POU5F1, BRD3, CTBP1, ZBTB17, STAT1, SRF, HIC1, ERG, ZBTB21, MYC, SMARCA4, TOP1, GRHL3, NKX2-1, GABPA, STAT3, UBN1, NKX3-1, RCOR1, VDR, NR3C1, CEBPB, ESRRA, CREB1, FEZF1, GRHL2, SPI1, ZNF664, GATA2, FLI1, MRTFB, NFYB, ZIM3, RUNX1, NKX2-2, AFF4, ZNF335, ZFP37, SMARCC1, PRDM10, TWIST1, CREBBP, ZNF384, ZNF35, NOTCH1, RUNX2, ZSCAN30, OSR2, NRF1, ARNT, ATF2, PRDM9, ZNF518A, MAFB, CHD1, CDK8, FOS, CSNK2A1, ZEB1, CEBPD, SCRT2, PIAS1, KLF9, NUP98-HOXA9, MAFK, REST, ZNF479, ARID1A, POU2F3, ZHX1, HOXA9, PHIP, PRDM6, SMC3, ELL2, ZNF394, FOXA2, SS18, GTF2B, MAFF, ZNF30, FOXF1, ZNF574, HOXB13, KDM1A, RELA, NEUROD1, JUNB, AHR, OTX2, GATA3, HAND2, TLE3, SP7, TCF7L2, PKNOX1, BCL6B, ELF3, BRD2, AR, ZBTB40, ZNF324, ZNF366, BRD4, JUND, MAZ, BRCA1, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00413666