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Basic information

CohesinDB ID: CDBP00413673

Locus: chr21-16186787-16187211

Data sourse: ENCSR230ZWH, GSE138405, GSE206145, ENCSR000EDE, ENCSR000ECS

Cell type: RPE, Liver, HeLa-S3, Hela-Kyoto

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,SMC3,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 42% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 77%, "7_Enh": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, CHD8, FOXA2, POU5F1, MYCN, TOP2A, SOX2, SS18, NME2, FOXA1, ZNF205, SRF, CDK9, HOXB13, ZFHX2, SMARCC1, ERG, TWIST1, RELA, ZNF300, ZNF19, ASCL1, ZNF133, NEUROD1, AHR, MYC, SMARCA4, BRG1, GATA4, CHD7, PRDM1, GRHL3, ARNT, RAD21, HIF1A, OTX2, ZKSCAN2, GABPA, TAL1, MAX, SOX10, ETV6, GATA1, CDK8, STAT3, MED1, TLE3, NR2F2, TRIM28, PIAS1, KDM5B, OCA2, GRHL2, USF2, BRD2, CTCF, ELF3, SPI1, BAF155, BHLHE40, AR, GATA6, PAX3-FOXO1, NKX2-5, GATA2, ZBTB7A, EGLN2, ZNF366, FLI1, HSF1, ZNF777, BRD4, ZNF440, MRTFB, RBPJ

Target gene symbol (double-evidenced CRMs): USP25,NRIP1,HSPA13

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000155304, ENSG00000180530, ENSG00000155313,

eachgene

Deatailed information for cohesin site CDBP00413673