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Basic information

CohesinDB ID: CDBP00413677

Locus: chr21-16198035-16199514

Data sourse: GSE138405, GSE101921, GSE62063, ENCSR230ZWH

Cell type: Liver, Hela-Kyoto, HCAEC, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: NIPBL,Rad21,SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 42% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 54%, "5_TxWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CBX5, PPARG, CREM, TOP2A, SOX2, NME2, MAFF, SUZ12, ZNF485, SMARCC1, ERG, RELA, NEUROD1, ETS1, JUNB, NFIC, BRG1, RAD21, RUNX3, HIF1A, OTX2, ATF2, BATF3, GABPA, BATF, TAL1, NR3C1, KLF4, SETDB1, BRD2, JUN, MAFK, BAF155, SPI1, AR, GATA6, GATA2, NCOR1, ZNF605, BRD4, ZNF567, SMC1, AATF

Target gene symbol (double-evidenced CRMs): NRIP1,USP25,HSPA13

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000155304, ENSG00000180530, ENSG00000155313,

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Deatailed information for cohesin site CDBP00413677