- Basic information
- CohesinDB ID: CDBP00413684
- Locus: chr21-16211544-16212337
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Data sourse: ENCSR230ZWH, GSE138405, GSE126634, GSE165895, GSE206145, GSE152721, GSE62063, GSE126990, ENCSR917QNE
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Cell type: RPE, Hela-Kyoto, HFFc6, Liver, HAP1, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: NIPBL,Rad21,SMC1,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
42% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 48%,
"7_Enh": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, SOX2, FOXA1, SUZ12, ATF3, ZBTB44, PRDM1, IKZF3, TP63, MITF, ETV1, LMO2, MLL, OCA2, TP73, CTCF, TCF12, BAF155, GATA6, PDX1, RBPJ, BRD3, TOP2A, ZBTB17, ZBTB48, SRF, HIC1, HNF4G, ERG, ONECUT1, MYC, SMARCA4, ZNF84, RAD21, RXRA, NKX2-1, NKX3-1, NFE2, NR3C1, CREB1, SPI1, GATA2, INTS13, FLI1, RELB, MRTFB, RUNX1, CEBPA, NKX2-2, ZFX, SMARCC1, ZNF35, RUNX2, GATA4, ARNT, FOS, CDK8, ZEB1, PIAS1, EVI1, SP1, HNF4A, REST, ZBTB7A, ASH2L, PHIP, FOXP1, PRDM6, ZNF34, ZNF394, SKI, PPARG, SS18, ZSCAN16, WT1, ZBTB33, HOXB13, YY1, RELA, NEUROD1, JUNB, BRG1, HIF1A, OTX2, TAL1, MAX, GATA1, BCL11B, NR2F2, ZNF334, PHOX2B, BRD2, AR, NOTCH3, BRD4, JUND
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops