- Basic information
- CohesinDB ID: CDBP00413686
- Locus: chr21-16215187-16219420
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Data sourse: ENCSR000BTU, GSE206145-GSE177045, ENCSR230ZWH, ENCSR000BKV, ENCSR000EGW, GSE206145, ENCSR335RKQ, GSE62063, GSE206145-NatGen2015, GSE106870, ENCSR917QNE
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Cell type: MCF-7, RPE, Fibroblast, Ishikawa, A-549, K-562, CVI-hiPSC, Liver, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: NIPBL,Rad21,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
42% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 53%,
"5_TxWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF283, FOXA2, CEBPA, SS18, ZSCAN16, DUX4, FOXA1, HIC1, SMARCC1, YY1, RELA, ZNF384, ASCL1, NEUROD1, ATF3, MYC, BRG1, OSR2, RAD21, PRDM1, ISL1, BRCA1, ZBTB44, RXRA, OTX2, CHD7, PRDM9, TAL1, MAX, STAT3, PAX5, FOS, CDK8, RCOR1, NFE2, HAND2, NR3C1, CEBPB, SP7, NR2F2, ESR1, PITX3, FEZF1, ZNF334, PHOX2B, BRD2, NUP98-HOXA9, SP1, SPI1, ZNF664, HNF4A, AR, GATA6, REST, PRDM4, POU2F3, FLI1, ZNF777, PHIP, PRDM6, TEAD4, ZNF34, PDX1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: Serum_alkaline_phosphatase_levels
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops