- Basic information
- CohesinDB ID: CDBP00413695
- Locus: chr21-16240807-16242169
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Data sourse: ENCSR000BLD, ENCSR000BTU, GSE206145-GSE177045, ENCSR230ZWH, GSE138405, GSE126634, GSE105028, GSE101921, GSE152721, GSE62063, GSE206145, GSE68388, GSE97394, GSE94872, GSE64758, GSE73207
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Cell type: MCF-7, H1-hESC, Hela-Kyoto, HEK293T, TF-1, Ishikawa, HUVEC, HCAEC, Ramos, HUES64, Liver, HAP1, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
42% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 58%,
"7_Enh": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF660, SOX2, XBP1, FOXA1, LYL1, NFIC, ZBTB44, PRDM1, CHD7, MORC2, MECOM, TEAD1, TRIM28, ETV1, LMO2, ZNF561, JUN, TCF12, CTCF, EP300, BAF155, GATA6, PRDM4, SMC1, TEAD4, GLIS1, NANOG, POU5F1, ZBTB17, STAT1, SRF, HIC1, ERG, USP7, ETS1, MYC, SMARCA4, EOMES, RAD21, FOXP2, GRHL3, TOP1, PROX1, GABPA, NKX3-1, NFE2, LEF1, ZNF501, CEBPB, NR3C1, ZBTB11, CREB1, FEZF1, SPI1, HDAC2, GATA2, SIX2, FLI1, MRTFB, ZIM3, RUNX1, CTNNB1, SMC1A, CEBPA, EZH2phosphoT487, SMAD3, ZNF770, SMARCC1, PRDM10, RUNX2, ZSCAN30, GATA4, OSR2, SMAD2, CDK6, ATF2, SMAD4, FOXM1, CHD1, CDK8, CSNK2A1, CEBPD, ZMYM3, PIAS1, SMAD1, KLF9, TBX5, EVI1, NUP98-HOXA9, NIPBL, SP1, BCL11A, ZBTB7A, ARID1A, PHIP, TCF3, FOXP1, GLIS2, BCOR, PRDM6, SMC3, STAG1, STAG2, ZNF394, FOXA2, ZNF207, MEIS1, SS18, ZSCAN16, WT1, HOXB13, MPHOSPH8, KDM1A, YY1, RELA, JUNB, BRG1, ZIC2, HIF1A, OTX2, GATA3, TAL1, GATA1, TLE3, KLF4, BCL11B, SP7, NR2F2, TCF7L2, PKNOX1, BRD2, ELF3, T, AR, ZNF366, ZBTB42, BRD4, JUND, BRCA1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops