- Basic information
- CohesinDB ID: CDBP00413714
- Locus: chr21-16295739-16296369
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Data sourse: GSE206145-GSE177045, GSE86191, GSE206145, GSE206145-NatGen2015, GSE62063
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Cell type: MCF-7, RPE, Fibroblast, HCT-116, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 89%,
"5_TxWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, TRP47, OGG1, NEUROD1, FOXA2, GATA4, TOP2A, PRDM1, DUX4, ZBTB48, FOXA1, GABPA, JUN, ERG
- Target gene symbol (double-evidenced CRMs): NRIP1,USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000180530,
ENSG00000155313,
- Related loop:
chr21:15000000-15025000~~chr21:16275000-16300000,
chr21:15875000-15900000~~chr21:16275000-16300000,
chr21:15900000-15925000~~chr21:16275000-16300000,
chr21:16050000-16075000~~chr21:16275000-16300000,
chr21:16075000-16100000~~chr21:16275000-16300000,
chr21:16075000-16100000~~chr21:16300000-16325000,
chr21:16100000-16125000~~chr21:16275000-16300000,
chr21:16175000-16200000~~chr21:16275000-16300000,
chr21:16175000-16200000~~chr21:16300000-16325000,
chr21:16275000-16300000~~chr21:16400000-16425000,
chr21:16275000-16300000~~chr21:17250000-17275000,
chr21:16300000-16325000~~chr21:17250000-17275000,