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Basic information

CohesinDB ID: CDBP00413716

Locus: chr21-16302671-16303742

Data sourse: ENCSR000BTU, ENCSR230ZWH, GSE138405, GSE116868, GSE206145-NatGen2015, GSE62063, GSE126990, ENCSR917QNE

Cell type: Hela-Kyoto, Fibroblast, MB157, Ishikawa, Liver, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: NIPBL,Rad21,SMC1,SA2,Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 40% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 45%, "7_Enh": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, FOSL1, PGR, CHD8, PPARG, FOXA2, BRD3, ZNF263, SS18, SOX2, XBP1, GTF2B, STAT1, FOXA1, HLF, ZBTB33, HOXB13, SMARCC1, ERG, YY1, RELA, TFAP4, ZNF384, NEUROD1, ATF3, RUNX2, CDK6, SMARCA4, BRG1, RAD21, CHD7, ARNT, HIF1A, NRF1, RXRA, OTX2, HMGB2, GABPA, TAL1, MAX, XRCC5, NKX3-1, CDK8, NFE2, MED1, SFPQ, CSNK2A1, NCOA3, NR2F2, ZNF121, TEAD1, CREB1, PIAS1, NFE2L2, ESR1, KLF9, ZSCAN22, MYOD1, PHOX2B, JUN, NUP98-HOXA9, MAFK, BAF155, SP1, BCL11A, HNF4A, AR, TAF1, GATA2, REST, PRDM4, EGLN2, ZBTB42, NOTCH3, BRD4, JUND, FOXP1, E2F1, MYF5, BRCA1, RBPJ, EED

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00413716