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Basic information

CohesinDB ID: CDBP00413717

Locus: chr21-16304251-16305030

Data sourse: GSE62063, ENCSR230ZWH, ENCSR917QNE

Cell type: Liver, Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: NIPBL,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 40% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 55%, "5_TxWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, CBX5, ZNF660, SOX2, FOXA1, ATF3, NFIC, CHD7, PRDM1, ZBTB44, RUNX3, SMARCE1, PAX5, TP63, MITF, SFPQ, ELF1, ETV1, ESR1, OCA2, TP73, JUN, CTCF, TCF12, BAF155, EP300, IRF4, RFX5, E2F1, TEAD4, RBPJ, TFAP2C, NANOG, CHD8, BRD3, TOP2A, ZBTB17, DUX4, STAT1, SRF, HNF4G, ERG, ONECUT1, MYC, SMARCA4, RAD21, LHX2, RXRA, NKX2-1, BATF3, GABPA, STAT3, NKX3-1, VDR, NR3C1, CEBPB, CREB1, EZH2, GATA2, FLI1, ZNF777, MXI1, MRTFB, MYF5, EZH2phosphoT487, ZFX, POU4F2, SMAD3, SMARCC1, RUNX2, ARNT, ATF2, FOXM1, CHD1, CDK8, FOS, MED1, CSNK2A1, PML, PIAS1, KLF9, L3MBTL2, NUP98-HOXA9, MAFK, SP1, NIPBL, USF1, HNF4A, REST, ARID1A, ATF7, POU2F3, ASH2L, HOXA9, BCOR, FOXP1, PRDM6, FOXA2, MTA3, CREM, SS18, GTF2B, ZBTB33, CDK9, HOXB13, YY1, RELA, NEUROD1, JUNB, BRG1, HIF1A, OTX2, BATF, TAL1, MAX, ZSCAN26, TLE3, KLF4, SP7, NR2F2, PKNOX1, PHOX2B, T, BRD2, AR, EGLN2, NOTCH3, BRD4, JUND, BRCA1, FOSL2

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00413717