- Basic information
- CohesinDB ID: CDBP00413718
- Locus: chr21-16305493-16308786
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Data sourse: ENCSR000BTU, ENCSR230ZWH, GSE131956, GSE138405, GSE126634, ENCSR404BPV, GSE152721, GSE62063, ENCSR198ZYJ, GSE126990, ENCSR917QNE
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Cell type: Hela-Kyoto, Neurons-H1, Ishikawa, GBM39, Liver, HAP1, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: NIPBL,SMC3,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 37%,
"1_TssA": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CBX5, ZNF660, SOX2, FOXA1, ATF3, NFIC, CHD7, PRDM1, ZBTB44, RUNX3, SMARCE1, PAX5, TP63, MITF, SFPQ, ELF1, ETV1, ESR1, OCA2, TP73, JUN, CTCF, TCF12, BAF155, EP300, IRF4, RFX5, E2F1, TEAD4, RBPJ, TFAP2C, NANOG, CHD8, BRD3, TOP2A, ZBTB17, DUX4, STAT1, SRF, HNF4G, ERG, ONECUT1, MYC, SMARCA4, RAD21, LHX2, RXRA, NKX2-1, BATF3, GABPA, STAT3, NKX3-1, VDR, NR3C1, CEBPB, CREB1, EZH2, GATA2, FLI1, ZNF777, MXI1, MRTFB, MYF5, EZH2phosphoT487, ZFX, POU4F2, SMAD3, SMARCC1, RUNX2, ARNT, ATF2, FOXM1, CHD1, CDK8, FOS, MED1, CSNK2A1, PML, PIAS1, KLF9, L3MBTL2, NUP98-HOXA9, MAFK, SP1, NIPBL, USF1, HNF4A, REST, ARID1A, ATF7, POU2F3, ASH2L, HOXA9, BCOR, FOXP1, PRDM6, FOXA2, MTA3, CREM, SS18, GTF2B, ZBTB33, CDK9, HOXB13, YY1, RELA, NEUROD1, JUNB, BRG1, HIF1A, OTX2, BATF, TAL1, MAX, ZSCAN26, TLE3, KLF4, SP7, NR2F2, PKNOX1, PHOX2B, T, BRD2, AR, EGLN2, NOTCH3, BRD4, JUND, BRCA1, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops