- Basic information
- CohesinDB ID: CDBP00413725
- Locus: chr21-16325876-16326019
-
Data sourse: GSE120943, GSE98367
-
Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 91%,
"5_TxWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CHD8, FOXA2, ZFX, FOXA1, DDX5, SMARCC1, ERG, ONECUT1, GRHL3, TAL1, ZSCAN4, CHD1, TEAD1, SCRT2, BAF155, AR, SCRT1, CTBP2, BRD4, ZNF337, BRCA1
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000155313,
- Related loop:
chr21:15875000-15900000~~chr21:16325000-16350000,
chr21:15893462-15895497~~chr21:16329695-16331504,
chr21:15893488-15895469~~chr21:16329708-16331761,
chr21:15893524-15897646~~chr21:16329660-16331732,
chr21:15893561-15895465~~chr21:16329691-16331745,
chr21:15894096-15895371~~chr21:16329800-16331227,
chr21:15900000-15925000~~chr21:16325000-16350000,
chr21:15975000-16000000~~chr21:16325000-16350000,
chr21:15976127-15978155~~chr21:16329665-16331731,
chr21:16000000-16025000~~chr21:16325000-16350000,
chr21:16001839-16003762~~chr21:16329724-16331264,
chr21:16001977-16003846~~chr21:16329691-16331745,
chr21:16001998-16003844~~chr21:16329695-16331504,
chr21:16002031-16003807~~chr21:16329708-16331692,
chr21:16002041-16004416~~chr21:16329708-16331761,
chr21:16002066-16003798~~chr21:16329704-16331395,
chr21:16002070-16004771~~chr21:16329660-16331732,
chr21:16002137-16004536~~chr21:16329715-16331630,
chr21:16002506-16003755~~chr21:16329734-16331645,
chr21:16050000-16075000~~chr21:16325000-16350000,
chr21:16075000-16100000~~chr21:16300000-16325000,
chr21:16075000-16100000~~chr21:16325000-16350000,
chr21:16080950-16084349~~chr21:16329708-16331761,
chr21:16081162-16083633~~chr21:16329712-16331679,
chr21:16081466-16083821~~chr21:16329193-16331742,
chr21:16081489-16083755~~chr21:16329665-16331731,
chr21:16081561-16084216~~chr21:16329470-16331627,
chr21:16081615-16083855~~chr21:16329435-16331632,
chr21:16081617-16086246~~chr21:16329660-16331732,
chr21:16081629-16084204~~chr21:16329429-16331686,
chr21:16081660-16083550~~chr21:16329692-16331743,
chr21:16081669-16083822~~chr21:16329695-16331504,
chr21:16081683-16083473~~chr21:16329752-16331396,
chr21:16081685-16083647~~chr21:16329574-16331680,
chr21:16081687-16083628~~chr21:16329691-16331745,
chr21:16081744-16083647~~chr21:16329711-16331318,
chr21:16081934-16083365~~chr21:16329763-16331425,
chr21:16081952-16083289~~chr21:16329800-16331227,
chr21:16175000-16200000~~chr21:16300000-16325000,
chr21:16175000-16200000~~chr21:16325000-16350000,
chr21:16193491-16195671~~chr21:16329708-16331761,
chr21:16193509-16195554~~chr21:16329695-16331504,
chr21:16193510-16195687~~chr21:16329193-16331742,
chr21:16193567-16195698~~chr21:16329660-16331732,
chr21:16300000-16325000~~chr21:17250000-17275000,
chr21:16325000-16350000~~chr21:16425000-16450000,
chr21:16325000-16350000~~chr21:16500000-16525000,
chr21:16325000-16350000~~chr21:16575000-16600000,
chr21:16325000-16350000~~chr21:16600000-16625000,
chr21:16325000-16350000~~chr21:16625000-16650000,
chr21:16325000-16350000~~chr21:16825000-16850000,
chr21:16325000-16350000~~chr21:16975000-17000000,
chr21:16325000-16350000~~chr21:17050000-17075000,
chr21:16325000-16350000~~chr21:17125000-17150000,
chr21:16325000-16350000~~chr21:17250000-17275000,
chr21:16329660-16331732~~chr21:17044687-17046393,
chr21:16329708-16331761~~chr21:17269501-17271331,
chr21:16329712-16331679~~chr21:17269387-17271333,