- Basic information
- CohesinDB ID: CDBP00413745
- Locus: chr21-16407671-16408939
-
Data sourse: ENCSR230ZWH, GSE138405, ENCSR000BLY, ENCSR000EHW, GSE206145, ENCSR000EHX, GSE138105, GSE126990, ENCSR917QNE
-
Cell type: RPE, Hela-Kyoto, SLK, SK-N-SH, Liver
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21,SA2,Mau2,SMC3
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 83%,
"7_Enh": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, SMARCA2, ZNF496, FOXA1, ZFHX2, ATF3, ZBTB44, PRDM1, SMARCE1, PAX5, ELF1, TRIM28, TEAD1, ETV1, ESR1, OCA2, PITX3, CTCF, JUN, EP300, BAF155, GATA6, U2AF2, TEAD4, TFAP2C, NANOG, ZNF263, TOP2A, ZNF778, ZSCAN21, ZNF317, DUX4, ZBTB17, ZBTB48, SRF, ERG2, HIC1, HNF4G, ERG, USP7, ZNF341, ONECUT1, MYC, TOP1, RAD21, LHX2, RXRA, GABPA, STAT3, UBN1, NKX3-1, RCOR1, NR3C1, CREB1, EBF3, MRTFA, SPI1, GATA2, FLI1, MXI1, MRTFB, NCOA2, RUNX1, CEBPA, ERG3, SMARCC1, RUNX2, ARNT, CSNK2A1, PIAS1, SP1, HNF4A, REST, CTBP2, SRSF9, SMC3, ELL2, ZNF394, FOXA2, SS18, ZSCAN16, GTF2B, WT1, ZBTB33, HOXB13, KDM1A, YY1, RELA, NEUROD1, BRG1, ISL1, HIF1A, OTX2, GATA3, TAL1, MAX, GATA1, HAND2, NR2F2, TCF7L2, PHOX2B, AR, TAF1, YAP1, EGLN2, ZNF366, EGR1, BRD4, JUND, TBX2
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000155313,
- Related loop:
chr21:15725000-15750000~~chr21:16400000-16425000,
chr21:16000000-16025000~~chr21:16400000-16425000,
chr21:16175000-16200000~~chr21:16400000-16425000,
chr21:16275000-16300000~~chr21:16400000-16425000,
chr21:16400000-16425000~~chr21:16500000-16525000,
chr21:16400000-16425000~~chr21:16525000-16550000,
chr21:16400000-16425000~~chr21:16575000-16600000,
chr21:16400000-16425000~~chr21:16600000-16625000,
chr21:16400000-16425000~~chr21:17250000-17275000,