Deatailed information for cohesin site CDBP00413748

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  • Basic information
  • CohesinDB ID: CDBP00413748
  • Locus: chr21-16418688-16425215
  • Data sourse: GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE126634, ENCSR000BLY, GSE25021, GSE108869, ENCSR917QNE, GSE165895, ENCSR000BTU, GSE138405, GSE76893, GSE101921, GSE152721, GSE138105, GSE130135, GSE116344, ENCSR703TNG, ENCSR000BLS, ENCSR000EHW, GSE206145, GSE62063, ENCSR000EHX, ENCSR635OSG, ENCSR000BTQ, GSE131956, ENCSR000EDE, GSE68388, GSE83726, GSE126990, ENCSR000ECS
  • Cell type: MCF-7, RPE, Hela-Kyoto, RH4, HEK293T, Hep-G2, SLK, Ishikawa, HCAEC, Ramos, HeLa-S3, GBM39, SK-N-SH, Liver, HAP1, HuCC-T1, HFFc6
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 16% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.800
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TSS,TES,Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 40% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 25%, "1_TssA": 25%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, LCORL, ZNF660, ZSCAN5C, SOX2, NME2, XBP1, FOXA1, ZNF221, ZNF596, KDM3A, TFAP4, ZNF529, ZFHX2, MEN1, ATF3, NFIC, ZNF362, ZBTB44, PRDM1, CHD7, WDHD1, MORC2, ZNF273, ZNF189, SMARCE1, MZF1, TP63, SFPQ, MYOG, ELF1, TRIM28, TEAD1, ETV1, SNAI2, KLF10, ZBTB49, ESR1, ZNF624, ZNF217, PITX3, ZNF571, USF2, ZNF561, CTCF, JUN, TCF12, BAF155, EP300, ZNF695, ZNF577, SOX5, GATA6, PAX8, SOX4, PRDM4, TRIM24, RFX5, E2F1, NR5A2, SMC1, ZNF350, TEAD4, FOXA3, ZNF677, KLF3, GATAD2A, EHMT2, RBPJ, TFAP2C, GTF2F1, PDX1, CHD8, BRD3, MYCN, POU5F1, TOP2A, ZSCAN21, ZBTB17, ZBTB48, ZNF317, STAT1, HIC1, TBP, HNF4G, ERG, ZNF300, HOXC5, ASCL1, OGG1, ETS1, MYC, ZNF626, SMARCA4, ONECUT1, ZKSCAN2, RAD21, FOXP2, LHX2, GRHL3, RXRA, NKX2-1, GABPA, STAT3, XRCC5, UBN1, NKX3-1, RCOR1, ZNF639, NR3C1, CEBPB, ESRRA, ZNF750, CREB1, TBL1XR1, KLF8, GRHL2, FEZF1, ZNF652, EBF3, TRPS1, GABPB1, ZHX2, MIXL1, ZNF664, HDAC2, GATA2, ZNF182, ZNF644, FLI1, DRAP1, MXI1, ZNF418, MRTFB, NFYB, ZNF554, MYF5, ETV5, RUNX1, CBX1, SMC1A, CEBPA, NKX2-2, ZBTB24, ZNF335, ZNF534, ZFX, POU4F2, SIN3A, AFF4, ZBTB12, SMAD3, ZFP37, ZNF513, SMARCC1, PRDM10, TWIST1, ZNF18, CREBBP, ZNF35, ZNF384, ZXDC, RUNX2, CDK6, ZSCAN30, OSR2, GR, ZNF184, ZNF280A, ARNT, NRF1, NFIB, SMAD4, NFYA, ZEB2, PBX3, MAFB, ZNF10, CHD1, CDK8, FOXM1, FOS, MED1, CSNK2A1, TEAD3, CEBPD, SCRT2, PIAS1, ZNF680, KLF9, ZNF37A, NUP98-HOXA9, USF1, SP1, TFAP2A, GSPT2, HNF4A, BCL11A, MAFK, IKZF5, REST, ARID1A, ZHX1, ASH2L, HOXA9, CTBP2, PHIP, ZNF605, FOXP1, PRDM6, SMC3, ELL2, ZNF34, STAG1, STAG2, MLLT1, ZNF394, TRP47, FOXA2, ZNF225, CHD2, SS18, NFATC1, ZNF600, ZNF44, GTF2B, WT1, ZNF692, MAFF, FOXF1, ZNF662, ZBTB33, CDK9, YY2, HOXB13, KDM1A, YY1, RELA, NEUROD1, JUNB, BRG1, ISL1, ZNF830, TCF4, HIF1A, SP140, OTX2, GATA3, TAL1, MAX, ZNF613, NRIP1, ZNF143, GATA1, HAND2, TLE3, KLF4, SP7, NCOA3, NR2F2, ZNF544, TCF7L2, NR2F1, NEUROG2, KDM5B, TP53, PKNOX1, ZBTB6, MYOD1, PHOX2B, BRD2, ELF3, AR, TAF1, ZNF324, EGLN2, ZBTB42, ZNF366, ZBTB26, HSF1, NOTCH3, BRD4, SCRT1, JUND, CLOCK, CUX1, MAZ, NCOR1, TBX2, BRCA1, AHR
  • Target gene symbol (double-evidenced CRMs): USP25
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 40
  • Related genes and loops
  • Related gene: ENSG00000155313,
  • Related loop: chr21:15725000-15750000~~chr21:16400000-16425000, chr21:15985364-15987155~~chr21:16418172-16420244, chr21:16000000-16025000~~chr21:16400000-16425000, chr21:16175000-16200000~~chr21:16400000-16425000, chr21:16275000-16300000~~chr21:16400000-16425000, chr21:16325000-16350000~~chr21:16425000-16450000, chr21:16400000-16425000~~chr21:16500000-16525000, chr21:16400000-16425000~~chr21:16525000-16550000, chr21:16400000-16425000~~chr21:16575000-16600000, chr21:16400000-16425000~~chr21:16600000-16625000, chr21:16400000-16425000~~chr21:17250000-17275000, chr21:16418634-16420797~~chr21:17269397-17271405, chr21:16425000-16450000~~chr21:17250000-17275000,
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