- Basic information
- CohesinDB ID: CDBP00413773
- Locus: chr21-16521711-16523551
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR501LQA, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE25021, ENCSR330ELC, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, GSE165895, GSE86191, GSE138405, GSE76893, GSE101921, ENCSR806UKK, GSE135093, GSE206145-NatGen2015, ENCSR703TNG, ENCSR199XBQ, ENCSR895JMI, ENCSR193NSH, ENCSR768DOX, GSE206145, ENCSR247LSH, ENCSR807WAC, ENCSR000EHX, ENCSR748MVX, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, ENCSR000HPG, ENCSR676MJK, ENCSR335RKQ, ENCSR000EDE, GSE126990, ENCSR000ECS
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Cell type: MCF-7, H1-hESC, HMEC, Fibroblast, HCT-116, Hela-Kyoto, RPE, A-549, HeLa-S3, HUES64, IMR-90, SK-N-SH, Liver, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 18% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 82%,
"5_TxWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF394, FOXO1, RUNX1, PGR, SMC1A, FOXA2, MAFF, DUX4, FOXA1, FOXF1, HOXB13, PRDM10, ERG, HNF4G, RELA, ZNF384, JUNB, ATF3, ZNF341, GATA4, OSR2, RAD21, PRDM1, PBX4, HIF1A, ARNT, SOX11, TOP1, GATA3, ATF2, GABPA, MAX, TP63, NKX3-1, FOS, CDK8, MED1, TLE3, NR3C1, CEBPB, ESRRA, TEAD1, CREB1, PIAS1, SCRT2, STAG1, ESR1, GRHL2, JUN, CTCF, MAFK, EP300, BAF155, HNF4A, AR, ZBTB40, GATA2, ARID1A, PRDM4, EGLN2, ZNF366, POU2F3, DEK, ASH2L, BRD4, JUND, FOXP1, SMC1, SMC3, STAG2, ZNF316
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 22
- Related genes and loops