- Basic information
- CohesinDB ID: CDBP00413801
- Locus: chr21-16604508-16606674
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Data sourse: ENCSR230ZWH, GSE138405, GSE126634, ENCSR000BLY, ENCSR404BPV, ENCSR000EHW, GSE152721, ENCSR198ZYJ, ENCSR000EHX, ENCSR917QNE
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Cell type: Hela-Kyoto, Neurons-H1, SK-N-SH, Liver, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SMC3,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 55%,
"7_Enh": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU5F1, ZSCAN16, FOXA1, HOXB13, ERG, ONECUT1, ISL1, NKX3-1, TLE3, CEBPB, PIAS1, PHOX2B, BAF155, EP300, AR, GATA6, GATA2, POU2F3, CTBP2, FOXP1
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000155313,
- Related loop:
chr21:15875000-15900000~~chr21:16600000-16625000,
chr21:16050000-16075000~~chr21:16575000-16600000,
chr21:16075000-16100000~~chr21:16575000-16600000,
chr21:16075000-16100000~~chr21:16600000-16625000,
chr21:16081162-16083633~~chr21:16607552-16609634,
chr21:16125000-16150000~~chr21:16600000-16625000,
chr21:16175000-16200000~~chr21:16575000-16600000,
chr21:16175000-16200000~~chr21:16600000-16625000,
chr21:16200000-16225000~~chr21:16600000-16625000,
chr21:16325000-16350000~~chr21:16575000-16600000,
chr21:16325000-16350000~~chr21:16600000-16625000,
chr21:16400000-16425000~~chr21:16575000-16600000,
chr21:16400000-16425000~~chr21:16600000-16625000,
chr21:16450000-16475000~~chr21:16575000-16600000,
chr21:16450000-16475000~~chr21:16600000-16625000,
chr21:16453706-16455321~~chr21:16607527-16609497,
chr21:16453738-16455573~~chr21:16607762-16609529,
chr21:16453760-16455329~~chr21:16607672-16609536,
chr21:16453967-16455273~~chr21:16607552-16609634,
chr21:16575000-16600000~~chr21:16825000-16850000,
chr21:16575000-16600000~~chr21:16850000-16875000,
chr21:16575000-16600000~~chr21:17800000-17825000,
chr21:16607527-16609497~~chr21:17044740-17046062,