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Basic information

CohesinDB ID: CDBP00413802

Locus: chr21-16607375-16609815

Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR501LQA, GSE126634, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE105028, GSE103477, GSE25021, ENCSR330ELC, GSE108869, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE115602, GSE122299, GSE138405, GSE76893, GSE101921, ENCSR806UKK, GSE135093, GSE152721, GSE206145-NatGen2015, GSE112028, GSE130135, ENCSR199XBQ, ENCSR703TNG, GSE106870, GSE116344, GSE138105, GSE145327, GSE94872, ENCSR895JMI, ENCSR000EEG, ENCSR193NSH, ENCSR768DOX, ENCSR000BLS, ENCSR000EHW, GSE85526, ENCSR000ECE, ENCSR247LSH, ENCSR000BMY, ENCSR000EHX, ENCSR620NWG, ENCSR748MVX, ENCSR767DFK, ENCSR807WAC, ENCSR495WGO, ENCSR981FDC, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, GSE105004, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE131956, ENCSR000HPG, ENCSR676MJK, ENCSR335RKQ, ENCSR054FKH, ENCSR000EDE, GSE68388, GSE206145, GSE126990, GSE50893, ENCSR000ECS, ENCSR481YWD

Cell type: RH4, GM2610, SLK, CVB-hiPSC, CVI-hiPSC, Liver, HuCC-T1, H9-hESC, RPE, GM2630, HMEC, Fibroblast, HEKn, Ishikawa, GM12890, HeLa-S3, IMR-90, H1-hESC, GM12878, GM2588, GBM39, SK-N-SH, HeLa-Tet-On, THP-1, HUES64, MCF-7, Hela-Kyoto, MCF-10A, HEK293T, Hep-G2, A-549, HUVEC, HCAEC, HeLa, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 41% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.600

Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 40% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 67%, "5_TxWk": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: AR, HIF1A, NOTCH3, FOXA1, SPI1, ZNF19

Target gene symbol (double-evidenced CRMs): USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 43

Related genes and loops

Related gene: ENSG00000155313,

eachgene

Deatailed information for cohesin site CDBP00413802