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Basic information

CohesinDB ID: CDBP00413806

Locus: chr21-16624524-16624939

Data sourse: ENCSR000BTU, GSE126634, ENCSR000BLY, ENCSR000EHW, ENCSR000EHX

Cell type: Ishikawa, HAP1, SK-N-SH

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SMC3,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 40% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 71%, "5_TxWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZSCAN5C, ZNF660, SOX2, XBP1, FOXA1, SUZ12, NFIC, ZBTB44, ZNF736, ESR1, PITX3, TCF12, BAF155, EP300, PRDM4, ZNF423, TEAD4, PDX1, EED, CHD8, POU5F1, MYCN, ZNF263, ZBTB17, ZBTB48, HIC1, ZNF300, HOXC5, ERG, PBX1, ZNF341, MYC, SMARCA4, RAD21, GABPA, RCOR1, NR3C1, CEBPB, CREB1, FEZF1, EBF3, SPI1, GATA2, FLI1, MXI1, CEBPA, NKX2-2, ZNF335, POU4F2, ZNF770, ZNF513, SMARCC1, PRDM10, TWIST1, GATA4, OSR2, ARNT, FOXM1, MAFB, CEBPD, SCRT2, PIAS1, BCL11A, REST, POU2F3, CTBP2, PHIP, TCF3, FOXP1, PRDM6, PPARG, FOXA2, EBF1, CHD2, ZNF692, GTF2B, WT1, ZSCAN16, HOXB13, KDM1A, ISL1, HIF1A, OTX2, GATA3, MAX, HAND2, TLE3, BCL11B, SP7, TCF7L2, PHOX2B, BRD2, ZNF843, AR, ZNF324, ZNF366, ZBTB42, NOTCH3, SCRT1, BRD4, TBX2, BRCA1

Target gene symbol (double-evidenced CRMs): USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000155313,

eachgene

Deatailed information for cohesin site CDBP00413806