- Basic information
- CohesinDB ID: CDBP00413839
- Locus: chr21-16837168-16839032
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Data sourse: GSE138405, GSE126634, GSE206145, GSE152721, GSE206145-NatGen2015, GSE138105, GSE126990
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Cell type: RPE, Hela-Kyoto, Fibroblast, SLK, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Mau2,SA1,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 60%,
"7_Enh": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, PPARG, FOXA2, NKX2-2, TOP2A, SOX2, DUX4, ESR2, FOXF1, FOXA1, ERG, RELA, ZNF384, ZNF90, SMARCA4, GATA4, ZNF362, ISL1, LHX2, ARNT, HIF1A, PBX4, GATA3, BATF3, TAL1, PBX3, UBN1, NKX3-1, FOS, ZNF143, MAFB, STAT3, MAX, NR3C1, CEBPB, SP7, TEAD1, ETV1, NEUROG2, SCRT2, EZH2, ESR1, PHOX2B, JUN, CTCF, MAFK, AR, GATA2, SIX2, BRD4, SCRT1, ZNF766, PRDM6, BRCA1, PDX1, ZNF316
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 11
- Related genes and loops