- Basic information
- CohesinDB ID: CDBP00413847
- Locus: chr21-16891603-16892319
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Data sourse: ENCSR000BTU, GSE206145-GSE177045, GSE138405, GSE206145, GSE206145-NatGen2015, GSE126990, GSE165895
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Cell type: MCF-7, RPE, Hela-Kyoto, Fibroblast, Ishikawa, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: NIPBL,Rad21,SMC1,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 76%,
"9_Het": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, NANOG, CHD8, PPARG, CBX3, FOXA2, CEBPA, PGR, SOX2, NME2, GTF2B, SMAD3, FOXF1, FOXA1, HOXB13, SMARCC1, ZFHX2, ERG, RELA, NFIC, SMARCA4, EOMES, CHD7, GRHL3, HIF1A, ARNT, OTX2, NKX2-1, GATA3, GABPA, TAL1, STAT3, FOS, MED1, NR3C1, CEBPB, TEAD1, CEBPD, EZH2, TP53, ESR1, KLF9, GRHL2, MRTFA, EGR2, ELF3, JUN, TCF12, SP1, EP300, RXR, GATA2, YAP1, EGLN2, EGR1, FLI1, BRD4, MRTFB, TEAD4
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops