- Basic information
- CohesinDB ID: CDBP00413861
- Locus: chr21-16977257-16977401
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 83%,
"7_Enh": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF394, GLIS1, CHD8, CEBPA, NKX2-2, ZNF660, FOXA2, SOX2, ZFX, TEAD4, ZNF263, WT1, ZBTB48, PATZ1, FOXF1, HLF, ZNF770, ZNF574, FOXA1, HIC1, ZNF513, HOXB13, SMARCC1, PRDM10, ERG, KDM1A, RELA, NEUROD1, ONECUT1, SMARCA4, OSR2, CHD7, SP140, PRDM1, ARNT, LHX2, ZIC2, OTX2, ZBTB44, ZNF189, TP63, NKX3-1, ZSCAN4, RCOR1, KLF4, CEBPB, CEBPG, ZEB1, KLF5, ZNF121, CEBPD, ETV1, KLF6, TCF7L2, ESR1, PKNOX1, TP73, FEZF1, NFKB1, BRD2, ZNF843, AR, GATA2, REST, ZNF366, ZNF280D, FLI1, PHIP, PRDM6, KLF3, PDX1, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops