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Basic information

CohesinDB ID: CDBP00413870

Locus: chr21-17044135-17046074

Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE104888, ENCSR230ZWH, GSE72082, ENCSR501LQA, GSE126634, GSE116868, ENCSR760NPX, ENCSR000BLY, ENCSR404BPV, ENCSR150EFU, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, ENCSR330ELC, ENCSR000EDW, GSE108869, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE165895, GSE25021, GSE93080, GSE122299, GSE115250, GSE138405, GSE76893, GSE101921, ENCSR806UKK, GSE135093, GSE152721, ENCSR198ZYJ, GSE206145-NatGen2015, GSE112028, GSE130135, ENCSR199XBQ, ENCSR703TNG, GSE116344, GSE138105, GSE94872, ENCSR895JMI, ENCSR000EEG, ENCSR193NSH, ENCSR768DOX, ENCSR000BLS, ENCSR000EHW, GSE85526, ENCSR000ECE, ENCSR247LSH, ENCSR000BMY, ENCSR000EHX, ENCSR620NWG, ENCSR635OSG, ENCSR748MVX, ENCSR767DFK, ENCSR495WGO, ENCSR807WAC, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR000BTQ, GSE55407, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, GSE62063, ENCSR944ZCT, GSE131956, GSE110061, GSE129526, ENCSR000HPG, ENCSR335RKQ, ENCSR537EFT, ENCSR000EDE, GSE68388, GSE206145, ENCSR981FDC, GSE126990, GSE50893, ENCSR000ECS

Cell type: MDM, RH4, GM2610, SLK, Liver, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, HEKn, Ishikawa, HeLa-S3, IMR-90, DKO, HFFc6, H1-hESC, MB157, GM12878, GM12891, GM2588, GBM39, SK-N-SH, HeLa-Tet-On, THP-1, HUES64, MCF-7, Ramos, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, Neurons-H1, A-549, HUVEC, HCAEC, TC-71, OCI-AML-3, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 40% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.544

Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 31% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 91%, "5_TxWk": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: AR, GATA6, NKX2-5, GATA2, GATA1, ZBTB7A, EOMES, ETV1, GATA4, ISL1, FOXA1, GATA3, T, HOXB13, SPI1, RCOR1, KDM1A

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 10

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00413870