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Basic information

CohesinDB ID: CDBP00413872

Locus: chr21-17049043-17049734

Data sourse: GSE67783, GSE86191, GSE116868, GSE206145, GSE206145-NatGen2015

Cell type: RPE, Fibroblast, HCT-116, MB157, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 31% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 61%, "9_Het": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, TRP47, SMC1A, CHD8, MYCN, POU5F1, TOP2A, KDM4C, ZFX, XBP1, ZBTB48, WT1, TET2, ERG, RELA, MYC, SP140, GRHL3, APC, ZNF736, MED1, CEBPB, NCOA3, TRIM28, ESR1, SETDB1, CTCF, SPI1, AR, GATA6, PAX3-FOXO1, RAD51, NOTCH3, BRD4, E2F1, MAZ, AATF, SMC3, STAG1, TFAP2C

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00413872