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Basic information

CohesinDB ID: CDBP00413886

Locus: chr21-17127343-17128869

Data sourse: ENCSR000BLD, ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE76893, ENCSR703TNG, GSE25021, GSE97394

Cell type: MCF-7, H1-hESC, HUES64

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 31% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 86%, "7_Enh": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: NANOG, PGR, CHD8, CBX1, SMC1A, SIN3A, SS18, CTBP1, TEAD4, SOX2, DUX4, ESR2, FOXA1, HOXB13, SMARCC1, ERG, RELA, CREBBP, ZXDC, ZNF384, AHR, SMARCA4, RAD21, CHD7, ARNT, HIF1A, GRHL3, NFIB, GATA3, GABPA, NRIP1, MED1, ARNTL, NR3C1, KLF4, NCOA3, ELF1, TEAD1, NR2F2, CREB1, PIAS1, TCF7L2, EZH2, ZNF217, ESR1, TP53, KLF9, GRHL2, TRPS1, CTCF, TCF12, BAF155, EP300, NIPBL, MNT, AR, TFAP2A, ZBTB40, GATA2, SCRT1, BRD4, MBD2, CLOCK, E2F1, CTBP2, NCOA2, TFAP2C

Target gene symbol (double-evidenced CRMs): .

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 8

Related genes and loops

Related gene:

eachgene

Deatailed information for cohesin site CDBP00413886