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Basic information

CohesinDB ID: CDBP00413897

Locus: chr21-17250615-17251384

Data sourse: GSE138405, GSE126990, ENCSR000ECS

Cell type: HeLa-S3, Hela-Kyoto

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC3,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 46% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 93%, "14_ReprPCWk": 3%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF391, ZNF660, ZNF101, PATZ1, FOXA1, ZNF221, ZFHX2, INSM2, NFIC, ZNF362, ZBTB44, PRDM1, IKZF3, ZNF189, ZSCAN4, ZNF629, TRIM28, KLF10, ESR1, PITX3, ZNF561, CTCF, TCF12, JUN, EP300, ZNF577, BAF155, PRDM4, RFX5, TEAD4, GLIS1, ZNF263, CTBP1, ZSCAN21, ZBTB17, HIC1, TBP, ERG, ZBTB21, TSHZ1, GRHL3, STAT3, RCOR1, ZNF639, CEBPB, CREB1, KLF8, FEZF1, EBF3, GATA2, ZFP37, ZNF513, ZNF18, SMARCC1, PRDM10, ZNF35, ZNF384, OSR2, ZNF184, SP3, PBX4, ATF2, ZEB2, ZNF518A, FOS, ZEB1, ZNF558, SCRT2, KLF9, SETDB1, BCL11A, ARID1A, ATF7, PHIP, PRDM6, SMC3, ZNF34, ZNF394, CHD2, SS18, ZNF600, ZSCAN16, ZNF692, WT1, ZNF30, FOXF1, ZNF574, HOXB13, JUNB, BRG1, ISL1, OTX2, GATA3, HAND2, TLE3, BCL11B, SP7, TCF7L2, PKNOX1, ZNF213, BCL6B, ZNF843, AR, ZNF324, ZNF366, ZNF280D, BRD4, JUND, ZSCAN23, ZNF24

Target gene symbol (double-evidenced CRMs): USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 8

Related genes and loops

Related gene: ENSG00000155313,

eachgene

Deatailed information for cohesin site CDBP00413897