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Basic information

CohesinDB ID: CDBP00413899

Locus: chr21-17263719-17264642

Data sourse: GSE206145-GSE177045, GSE115250

Cell type: MCF-7, TC-32

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 46% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 98%, "14_ReprPCWk": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: GLIS1, SMARCA2, FOXA2, EZH2phosphoT487, ZSCAN5C, POU5F1, SS18, SIN3A, CTBP1, ZBTB17, WT1, ZBTB48, FOXA1, FOXF1, HOXB13, SMARCC1, ZNF35, MEN1, BRG1, SMARCA4, OSR2, ZBTB44, PRDM1, GATA3, STAT3, MZF1, FOS, TLE3, NR3C1, TEAD1, CEBPD, ZNF217, ESR1, PKNOX1, KLF8, FEZF1, ZNF334, BCL6B, ZNF561, GRHL2, ZNF34, CTCF, NUP98-HOXA9, ZNF843, BCL11A, PHOX2B, BAF155, DPF2, GATA2, ZBTB42, SRSF9, PHIP, CTBP2, CUX1, PRDM6, BRCA1

Target gene symbol (double-evidenced CRMs): USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000155313,

eachgene

Deatailed information for cohesin site CDBP00413899