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Basic information

CohesinDB ID: CDBP00413901

Locus: chr21-17268861-17271187

Data sourse: ENCSR230ZWH, ENCSR000BSB, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR917QNE, GSE115602, GSE101921, ENCSR806UKK, GSE51234, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, ENCSR000EEG, ENCSR338DUC, ENCSR247LSH, GSE105004, ENCSR676MJK, GSE155324, ENCSR054FKH, ENCSR748MVX, ENCSR000ECS, GSE38411, ENCSR000BLD, GSE131577, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE135093, GSE106870, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE122299, GSE115250, GSE76893, GSE145327, GSE76815, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE131956, GSE110061, ENCSR000HPG, ENCSR335RKQ, ENCSR000EDE, GSE50893, ENCSR481YWD, GSE206145-GSE177045, GSE72082, ENCSR501LQA, ENCSR404BPV, GSE105028, ENCSR000EDW, ENCSR000EFJ, ENCSR000BTU, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, ENCSR768DOX, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR807WAC, GSE62063, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE68388, GSE126990

Cell type: MDM, RH4, GM2610, SLK, CVB-hiPSC, Liver, GP5d, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, HMEC, Fibroblast, HEKn, Ishikawa, GM12890, HeLa-S3, IMR-90, BCBL-1, K-562, GM18486, DKO, H1-hESC, SNYDER, GM18505, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, CNCCs-H9ESC, HeLa-Tet-On, THP-1, HUES64, MCF-7, GM12892, Ramos, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, HUVEC, HCAEC, GM19238, HeLa, CNCC-WT33iPSC, OCI-AML-3, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 57% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.389

Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 46% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 91%, "9_Het": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: GLIS1, SMC1A, CEBPA, POU5F1, ZNF660, TOP2A, SS18, STAG2, FOXA1, SRF, ZNF654, SAP130, CDK9, TRIM22, HOXB13, SMARCC1, RXRB, ARID3A, ZBTB2, JUNB, MYC, BRG1, SMARCA4, RAD21, OTX2, NKX2-1, PRDM9, ZNF8, STAT3, ZNF143, HMGXB4, RCOR1, CEBPG, CEBPB, TEAD3, TEAD1, ESR1, GRHL2, EBF3, PHOX2B, CTCF, MAFK, BAF155, BCL11A, MIXL1, ARID4B, POU2F3, SMC1, ZNF280A, SMC3, GTF2F1, STAG1, ZNF316

Target gene symbol (double-evidenced CRMs): USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 14

Related genes and loops

Related gene: ENSG00000155313,

eachgene

Deatailed information for cohesin site CDBP00413901