- Basic information
- CohesinDB ID: CDBP00413954
- Locus: chr21-17467390-17468651
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Data sourse: ENCSR167MTG, ENCSR000EEG, ENCSR230ZWH, GSE72082, GSE126634, ENCSR000BLS, GSE152721, ENCSR054FKH, GSE62063, ENCSR153HNT, ENCSR917QNE
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Cell type: Hep-G2, K-562, Liver, HAP1, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 50%,
"7_Enh": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, HMG20A, ZNF660, SOX2, MEIS2, ZNF101, FOXA1, HLF, RBFOX2, RXRB, ATF3, NFIC, ZFP64, ZNF362, ZBTB44, PRDM1, CHD7, MXD4, ZNF189, MITF, ZNF629, KLF5, ELF1, ZNF121, TRIM28, ETV1, TEAD1, KLF6, SNAI2, RCOR2, ESR1, USF2, JUN, CTCF, BAF155, EP300, SOX5, TEAD4, FOXA3, ZNF175, GATAD2A, PDX1, RBPJ, MLX, TFAP2C, NANOG, CHD8, BRD3, POU5F1, TOP2A, ZSCAN21, ZBTB17, DUX4, ZBTB48, SRF, GATAD1, SAP130, DDX5, HIC1, ARID3A, SP4, HNF4G, ERG, ETS1, SMARCA4, HOMEZ, RAD21, LHX2, GRHL3, ARID1B, PROX1, NKX2-1, RXRA, GABPA, ZNF614, NKX3-1, MIER3, NR2F6, NR3C1, CEBPB, CREB1, EZH2, KLF8, ZNF652, GABPB1, SPI1, TFE3, EHF, MIXL1, HDAC2, GATA2, ZNF644, MXD3, SIX2, FLI1, DRAP1, ZGPAT, NFIL3, ETV5, RUNX1, THAP11, BCL6, SMC1A, CEBPA, SOX13, ZFX, ZNF335, ZFP37, SP5, SMARCC1, PRDM10, MYBL2, RARA, ZNF384, GATA4, OSR2, ZNF184, ZNF48, ZNF518A, SMAD4, HMBOX1, ZNF10, FOS, CDK8, HMGXB4, MED1, TEAD3, SCRT2, PIAS1, ZMYM3, ZNF136, MAFK, USF1, SP1, BCL11A, HNF4A, IKZF5, REST, POU2F3, ASH2L, PHIP, FOXP1, PRDM6, ZNF34, ZNF394, SKI, PPARG, FOXA2, CREM, MIER2, ZSCAN16, WT1, ZNF30, ZBTB33, HOXB13, ZNF580, KDM1A, YY1, RELA, NEUROD1, AHR, OTX2, MAX, TLE3, CEBPG, SP7, NR2F2, TCF7L2, PHOX2B, ELF3, BRD2, KAT8, PHF5A, ARID4B, AR, ZNF366, ZNF280D, ZBTB26, JUND, BRD4, MAZ, DMAP1, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 8
- Related genes and loops