- Basic information
- CohesinDB ID: CDBP00413957
- Locus: chr21-17472166-17473558
-
Data sourse: ENCSR167MTG, ENCSR000EEG, ENCSR338DUC, ENCSR230ZWH, GSE67783, GSE72082, GSE86191, GSE132649, GSE76893, ENCSR000BLS, GSE206145, GSE206145-NatGen2015, ENCSR054FKH, GSE25021, ENCSR000EDW, ENCSR917QNE
-
Cell type: RPE, T-47D, Fibroblast, HCT-116, Hep-G2, Liver, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 81%,
"7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NFIA, HMG20A, SOX2, HNF1A, FOXA1, HLF, RBFOX2, RXRB, KDM3A, TFAP4, TSC22D4, ATF3, NFIC, THRB, PRDM1, MXD4, TP63, CDX2, TEAD1, ELF1, KLF6, SNAI2, KLF10, RCOR2, MBD4, JUN, TCF12, CTCF, BAF155, EP300, SOX5, GATA6, IRF4, RFX5, TEAD4, FOXA3, ZNF175, GATAD2A, PDX1, RBPJ, MLX, NANOG, POU5F1, HHEX, ZNF317, DUX4, ZBTB48, SRF, GATAD1, SAP130, ARID3A, TBP, HNF4G, ERG, SMARCC2, ETS1, MYC, ONECUT1, HOMEZ, RAD21, RXRA, PROX1, FOXK2, GABPA, STAT3, ZNF614, XRCC5, NKX3-1, RCOR1, MIER3, NR2F6, ZNF750, CEBPB, HNRNPL, CREB1, TBL1XR1, ZNF652, GABPB1, ZHX2, MIXL1, TFE3, ZSCAN2, HBP1, HDAC2, GATA2, SSRP1, ZNF644, DRAP1, ZGPAT, RELB, NFIL3, ETV5, RUNX1, THAP11, BCL6, SMC1A, CEBPA, SOX13, ZFX, TBX3, SP5, SMARCC1, MYBL2, RARA, ZNF384, NFYC, CREBBP, GATA4, PBX4, ARNT, ZNF48, ATF2, PRDM9, FOS, SMARCB1, HMGXB4, TGIF2, MED1, TEAD3, ZEB1, CEBPD, PIAS1, ZMYM3, ZNF3, MBD1, MAFK, SP1, NIPBL, HNF4A, ARID2, IKZF5, ARID1A, REST, ATF7, ASH2L, FOXP1, SMC3, STAG1, SKI, PPARG, FOXA2, CREM, CHD2, MIER2, GTF2B, MAFF, FOXF1, ZBTB33, TCF7, HOXB13, ZNF580, FOXO3, KDM1A, YY1, ZKSCAN1, JUNB, HIF1A, MAX, TLE3, KLF4, CEBPG, NR2F2, ZNF334, PHF5A, ELF3, KAT8, ARID4B, AR, NFKBIZ, TAF1, BHLHE40, EGR1, ZBTB26, BRD4, JUND, CUX1, MAZ, SMAD4.1D12, ZNF24, DMAP1, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 13
- Related genes and loops