- Basic information
- CohesinDB ID: CDBP00413958
- Locus: chr21-17475711-17476441
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Data sourse: ENCSR167MTG, ENCSR230ZWH, GSE67783, GSE72082, ENCSR000BLS, GSE206145, ENCSR054FKH, GSE50893, ENCSR917QNE
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Cell type: RPE, GM12892, Hep-G2, Liver, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 85%,
"7_Enh": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, HMG20A, FOXA1, RXRB, KDM3A, TFAP4, ATF3, RUNX3, MXD4, TEAD1, TRIM28, KLF6, RCOR2, ESR1, MLL, JUN, EP300, SOX5, GATA6, IRF4, FOXA3, ZNF175, GATAD2A, RBPJ, MLX, ZSCAN5D, ZBTB48, GATAD1, SAP130, HNF4G, ERG, MYC, HOMEZ, RAD21, RXRA, XRCC5, ZNF614, MIER3, NR2F6, VDR, CEBPB, HNRNPL, ZNF652, GABPB1, SPI1, MIXL1, TFE3, HDAC2, GATA2, ZNF644, DRAP1, ZGPAT, NFIL3, ETV5, THAP11, BCL6, CEBPA, SOX13, ZFX, RARA, ZNF384, NFYC, GATA4, SMAD4, HMGXB4, MED1, TEAD3, MYB, SP1, BCL11A, HNF4A, IKZF5, PPARG, FOXA2, EBF1, MIER2, ZBTB33, CDK9, ZNF580, KDM1A, YY1, RELA, MAX, SPIB, CEBPG, ELF3, KAT8, NFKBIZ, ARID4B, ZBTB26, JUND, BRD4, DMAP1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops