- Basic information
- CohesinDB ID: CDBP00413967
- Locus: chr21-17495559-17496326
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Data sourse: ENCSR230ZWH, GSE138405, GSE206145, GSE206145-NatGen2015, GSE130135
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Cell type: RPE, Hela-Kyoto, Fibroblast, HEK293T, Liver
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.933
- Subunit: Mau2,SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES,Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 69%,
"14_ReprPCWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOSL1, BCL6, FOXA2, NKX2-2, HMG20A, TOP2A, SOX13, TEAD4, CEBPA, ZNF317, POU5F1, DUX4, FOXA1, SAP130, ARID3A, ETV5, SMARCC1, KDM1A, YY1, PAX6, ONECUT1, NFIC, MYC, OSR2, HOMEZ, RAD21, PRDM1, GRHL3, RXRA, GATA3, STAT3, ZNF614, MAX, NKX3-1, HAND2, ZNF736, NR3C1, CEBPB, CEBPG, TEAD3, EZH2, ESR1, JUN, TCF12, CTCF, SP1, EP300, MIXL1, HNF4A, AR, SOX5, ARID4B, SPI1, ZNF644, BRD4, JUND, PRDM6, NFIL3, SMC3, FOXA3, GATAD2A, PDX1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops