- Basic information
- CohesinDB ID: CDBP00413968
- Locus: chr21-17496902-17498024
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Data sourse: ENCSR167MTG, ENCSR000EEG, GSE72082, ENCSR000BLS, GSE206145, GSE206145-NatGen2015, ENCSR054FKH, ENCSR000EDW
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Cell type: Hep-G2, Fibroblast, HEK293T
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SMC3,Rad21,SA2,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 67%,
"14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, BCL6, PPARG, HMG20A, LCORL, FOXA2, CEBPA, SOX13, CREM, GTF2B, FOXA1, ZNF134, SAP130, RXRB, HOXB13, HNF4G, KDM1A, RARA, GATA4, HOMEZ, RAD21, PRDM1, ARNT, PRDM9, SMAD4, PAX5, ZNF10, MIER3, NR2F6, CDX2, CEBPG, TEAD3, TEAD1, CREB1, EZH2, RCOR2, ELF3, RBM22, KAT8, EP300, SP1, HNF4A, AR, SOX5, HDAC2, ZNF644, ZBTB26, ASH2L, ZGPAT, JUND, CUX1, NFIL3, FOXA3, GATAD2A, ETV5, DMAP1
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops