- Basic information
- CohesinDB ID: CDBP00413969
- Locus: chr21-17498618-17499531
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Data sourse: GSE206145-GSE177045, GSE138405, GSE129526, ENCSR000BLY, GSE206145, GSE94872
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Cell type: MCF-7, RPE, Hela-Kyoto, HCT-116, HEK293T, HUVEC, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: Mau2,SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 67%,
"14_ReprPCWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, FOSL1, PGR, ZNF391, HMG20A, ZNF660, SOX2, MEIS2, HNF1A, PATZ1, FOXA1, ZNF101, RBFOX2, RXRB, PBX2, MLL4, ZFHX2, KDM3A, TFAP4, SIN3B, TSC22D4, ATF3, NFIC, THRB, ZNF362, HNRNPUL1, ZBTB44, IKZF3, MXD4, ZNF189, SMARCE1, PAX5, ZSCAN4, CDX2, ZNF629, KLF5, TEAD1, TRIM28, ELF1, KLF6, KLF10, RCOR2, ESR1, HNF1B, ZNF217, TP73, ZNF561, MBD4, CTCF, TCF12, JUN, BAF155, EP300, L3MBTL4, ZNF577, SOX9, SOX5, GATA6, DPF2, ZNF695, PRDM4, KLF3, FOXA3, ZNF175, TEAD4, GATAD2A, RBPJ, TFAP2C, MLX, GLIS1, NANOG, ZNF263, HHEX, TOP2A, CTBP1, ZSCAN21, ZBTB17, DUX4, ZBTB48, STAT1, SRF, GATAD1, SAP130, ARID3A, HIC1, ERG2, HNF4G, ERG, ZBTB21, PAX6, HOXC5, USP7, ZBTB8A, ZNF626, MYC, ETS1, SMARCC2, TSHZ1, ARID1B, RAD21, HOMEZ, LHX2, SMARCA4, ONECUT1, PROX1, NKX2-1, RXRA, GABPA, STAT3, ZNF614, NKX3-1, LEF1, MIER3, NR2F6, ZNF639, NR3C1, ZNF750, ESRRA, CEBPB, ZNF501, HNRNPL, CREB1, EZH2, TBL1XR1, KLF8, GRHL2, FEZF1, ZNF652, EBF3, TRPS1, GABPB1, ZHX2, HES1, MIXL1, TFE3, ZNF664, IRF1, ZSCAN2, HBP1, HDAC2, GATA2, ZNF644, DRAP1, ZGPAT, NFIL3, NCOA2, MRTFB, ETV5, RUNX1, THAP11, CTNNB1, BCL6, SMC1A, CEBPA, EZH2phosphoT487, SOX13, ZNF534, ZFX, SIN3A, SMAD3, ZBTB12, ZFP37, TBX3, ERG3, SP5, ZNF513, SMARCC1, PRDM10, ZNF18, MYBL2, RARA, ZNF384, ZNF35, CREBBP, ZSCAN30, GATA4, OSR2, ZNF184, GR, SP3, ARNT, PBX4, ZNF48, SMAD4, ZEB2, SP2, FOS, CDK8, SMARCB1, ZNF10, HMGXB4, MED1, TEAD3, ZEB1, ZXDB, ZNF558, SCRT2, PIAS1, CEBPD, ZNF3, NR1H2, KLF9, NCOA1, MAFK, NIPBL, TFAP2A, BCL11A, HNF4A, SP1, IKZF5, REST, OVOL3, ATF7, ASH2L, CTBP2, PHIP, GLIS2, FOXP1, PRDM6, SMC3, NCOR2, ZNF34, ETV4, ZNF394, SKI, PPARG, FOXA2, EBF1, CREM, PAF1, MEIS1, MIER2, ZSCAN16, ZNF692, WT1, MAFF, ZNF30, CHD2, ZNF662, ZNF574, TCF7, ZBTB33, CDK9, HOXB13, ZNF580, FOXO3, KDM1A, RELA, NEUROD1, JUNB, AHR, BRG1, BRCA1, TCF4, HIF1A, ZIC2, ZFP36, OTX2, GATA3, MAX, ZNF449, NRIP1, TLE3, KLF4, CEBPG, SP7, GFI1B, NR2F2, TCF7L2, NR2F1, KDM5B, TP53, PKNOX1, ZBTB6, ZNF213, MED, ZNF334, BCL6B, EGR2, BRD2, ELF3, ZNF843, KAT8, PHF5A, ARID4B, AR, NFKBIZ, BHLHE40, RXR, ZNF324, EGLN2, ZNF366, ZBTB42, HSF1, NCOR1, ZBTB26, BRD4, JUND, CUX1, MAZ, ZSCAN23, SMAD4.1D12, ZNF24, DMAP1, FOSL2
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops