- Basic information
- CohesinDB ID: CDBP00414030
- Locus: chr21-17730293-17731186
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Data sourse: GSE98367, GSE108869, GSE206145, GSE206145-NatGen2015, GSE120943, GSE103477, GSE111537, GSE116344, GSE126755
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Cell type: RPE, Fibroblast, RH4, Monocytes, OCI-AML-3, HeLa-S3, Neutrophil, THP-1, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: SMC3,Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
60% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 79%,
"7_Enh": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXA2, SP140, GRHL3, ESR1, DUX4, RNF2, ZBTB48, GATA3, CBX8
- Target gene symbol (double-evidenced CRMs): .
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 8
- Related genes and loops