- Basic information
- CohesinDB ID: CDBP00414037
- Locus: chr21-17774973-17776242
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Data sourse: ENCSR000BLD, GSE93080, ENCSR000DZP, GSE72082, GSE86191, ENCSR000BLY, ENCSR000BLS, GSE105028, GSE206145, ENCSR000BMY, ENCSR153HNT, GSE120943, GSE68388, GSE25021, GSE50893, GSE126755
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Cell type: RPE, GM12892, GM2630, H1-hESC, HCT-116, Monocytes, Hep-G2, SNYDER, GM12878, GM12891, GM2588, GM19238, HuCC-T1, SK-N-SH, K-562, Neutrophil, GM18486, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.800
- Subunit: SMC3,Rad21,SA1,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 58%,
"7_Enh": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, POU2F2, MAFG, FOXA2, EBF1, MTA2, GTF2B, STAT1, FOXA1, HOXB13, BCL3, PRDM10, ERG, YY1, RELA, NOTCH1, ZNF597, NFKB2, MYC, RUNX3, BATF, GABPA, ETV6, PAX5, IKZF1, HAND2, ELF1, BCLAF1, MYB, TRIM28, C11orf30, NFKB1, GABPB1, CTCF, TCF12, MAFK, BCL11A, SP1, TBX21, BHLHE40, EP300, SPI1, AR, DPF2, IRF4, ATF7, FLI1, IKZF2, BRD4, TCF3, BCOR, RELB, TEAD4, EED
- Target gene symbol (double-evidenced CRMs): USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 9
- Related genes and loops
- Related gene:
ENSG00000155313,
- Related loop:
chr21:14075000-14100000~~chr21:17775000-17800000,
chr21:14375000-14400000~~chr21:17775000-17800000,
chr21:15025000-15050000~~chr21:17775000-17800000,
chr21:15725000-15750000~~chr21:17775000-17800000,
chr21:17350000-17375000~~chr21:17775000-17800000,
chr21:17375000-17400000~~chr21:17775000-17800000,
chr21:17425000-17450000~~chr21:17775000-17800000,
chr21:17650000-17675000~~chr21:17750000-17775000,
chr21:17650000-17675000~~chr21:17775000-17800000,
chr21:17675000-17700000~~chr21:17775000-17800000,
chr21:17750000-17775000~~chr21:17900000-17925000,
chr21:17775000-17800000~~chr21:17900000-17925000,
chr21:17775000-17800000~~chr21:18100000-18125000,
chr21:17775000-17800000~~chr21:18875000-18900000,
chr21:17775000-17800000~~chr21:23825000-23850000,
chr21:17775000-17800000~~chr21:25175000-25200000,
chr21:17775000-17800000~~chr21:25450000-25475000,
chr21:17775000-17800000~~chr21:25725000-25750000,
chr21:17775000-17800000~~chr21:29000000-29025000,
chr21:17775000-17800000~~chr21:38225000-38250000,