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Basic information

CohesinDB ID: CDBP00414038

Locus: chr21-17779465-17779881

Data sourse: GSE126755, GSE120943, GSE68388, GSE98367

Cell type: Macrophage, Neutrophil, Monocytes, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: SMC3,Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 62%, "5_TxWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CBX5, ZNF496, SOX2, FOXA1, ZNF28, TSC22D4, LYL1, BMI1, NFIC, RUNX3, CHD7, CBFB, PAX5, BACH2, JMJD1C, MAF, KLF5, ELF1, TRIM28, BCLAF1, ZNF217, LMO2, USF2, JUN, CTCF, TCF12, EP300, SND1, DPF2, TRIM24, IRF4, RAD51, KMT2B, GTF2F1, RBPJ, EED, POU2F2, POU5F1, TOP2A, RUNX1T1, MTA2, DUX4, STAT1, NBN, ARID3A, ERG, ZNF597, NFKB2, ZNF341, MYC, ETS1, RAD21, BATF3, GABPA, STAT3, IKZF1, NFE2, NR3C1, CEBPB, STAT5B, KMT2A, CREB1, ARHGAP35, SPI1, EHF, GATAD2B, FLI1, SMARCA5, RELB, HEXIM1-CDK9, RUNX1, SMC1A, CEBPA, ERG3, TRIM22, MEF2A, CREBBP, PBX4, ARNT, BACH1, ATF2, HMBOX1, ETV6, FOXM1, PBX3, FOS, SUPT5H, CDK8, MED1, PML, CEBPD, MYB, SMAD1, SETDB1, STAT5A, RBM22, BCL11A, NIPBL, SP1, NR4A1, ATF7, ASH2L, TCF3, STAT2, MLLT1, STAG1, NFATC3, SKI, MEF2B, MTA3, EBF1, CREM, PAF1, NFATC1, ZBED1, GTF2B, MEF2C, TCF7, CDK9, BCL3, KDM1A, YY1, RELA, TARDBP, JUNB, SKIL, GATA3, BATF, TAL1, MAX, CEBPG, NR2F1, ZNF687, PKNOX1, TP53, NFKB1, TBX21, BHLHE40, TAF1, EGR1, IKZF2, BRD4, NOTCH3, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000155313,

eachgene

Deatailed information for cohesin site CDBP00414038