Browse_each

Basic information

CohesinDB ID: CDBP00414072

Locus: chr21-17930894-17931556

Data sourse: ENCSR000BLD, GSE93080, ENCSR000EAC, ENCSR000DZP, GSE104888, GSE67783, GSE86191, GSE110061, GSE129526, ENCSR000BLY, GSE105028, ENCSR000ECE, GSE50893, GSE116344, GSE25021, GSE108869, ENCSR000EDW

Cell type: RH4, GM10847, GM2610, HSPC, H9-hESC, GM2630, GM12890, HeLa-S3, GM2255, GM18486, GM18526, H1-hESC, SNYDER, GM18505, GM12878, GM12891, GM2588, SK-N-SH, GM19239, GM19099, MCF-7, GM12892, HCT-116, Hep-G2, GM19238, GM18951

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 9% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.711

Subunit: SMC3,Rad21,SA1,SMC1

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 78%, "9_Het": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZNF660, SOX2, FOXA1, PBX2, ATF3, CHD7, ZNF189, SFPQ, TRIM28, BCLAF1, SNAI2, LMO2, ESR1, OCA2, SMAD5, CTCF, TCF12, PAX8, IRF4, SMC1, TEAD4, GTF2F1, TFAP2C, RBPJ, POU2F2, CHD8, NANOG, MYCN, POU5F1, ZNF263, KDM4C, CDK7, ZBTB48, DUX4, STAT1, SRF, ERG, MYC, RAD21, GRHL3, GABPA, XRCC5, EZH2, GABPB1, SPI1, GATA2, GATAD2B, HCFC1, SMARCA5, RELB, MRTFB, RUNX1, SMC1A, CBX1, NKX2-2, ZFX, POU4F2, TET2, ERG3, TRIM22, ZBTB2, PBX3, SP2, ZEB1, MYB, PIAS1, SETDB1, BCL11A, GSPT2, SMC3, MLLT1, STAG1, GTF2B, WT1, ZNF574, CDK9, YY1, RELA, TARDBP, SP140, HIF1A, OTX2, MAX, SPIB, ZNF143, HAND2, NCOA3, TCF7L2, TP53, PKNOX1, NFKB1, BRD2, AR, EGLN2, HEXIM1, RB1, HSF1, NOTCH3, BRD4, MAZ, TBX2

Target gene symbol (double-evidenced CRMs): TMPRSS15

Function elements

Human SNPs: .

Number of somatic mutations (coding): 24

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154646,

eachgene

Deatailed information for cohesin site CDBP00414072