- Basic information
- CohesinDB ID: CDBP00414084
- Locus: chr21-18040660-18041642
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE126634, GSE116868, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE121355, GSE103477, GSE111537, GSE131606, GSE108869, ENCSR000EDW, GSE25021, ENCSR917QNE, GSE115602, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE143937, GSE122299, GSE115250, GSE138405, GSE76893, GSE101921, GSE152721, GSE51234, GSE206145-NatGen2015, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR703TNG, GSE106870, GSE116344, GSE138105, GSE145327, GSE94872, ENCSR000EEG, ENCSR338DUC, ENCSR000BLS, ENCSR000EHW, GSE85526, ENCSR000ECE, GSE62063, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE206145, GSE97394, GSE55407, ENCSR000BTQ, GSE105004, ENCSR167MTG, GSE131956, GSE110061, GSE129526, GSE155324, ENCSR054FKH, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS, GSE131577
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Cell type: MDM, RH4, GM2610, SLK, CVB-hiPSC, CVI-hiPSC, Liver, GP5d, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, HEKn, Ishikawa, GM12890, HeLa-S3, GM2255, K-562, GM18486, DKO, H1-hESC, SNYDER, MB157, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, CNCCs-H9ESC, HeLa-Tet-On, THP-1, HUES64, MCF-7, GM12892, Ramos, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, HUVEC, HCAEC, GM19238, HeLa, CNCC-WT33iPSC, OCI-AML-3, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 41% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.400
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
31% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 95%,
"5_TxWk": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, SMARCA4, ISL1, TEAD4, SOX11, OTX2, GATA3, TAL1, PHOX2B, TBX2, NUP98-HOXA9
- Target gene symbol (double-evidenced CRMs): TMPRSS15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 24
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154646,
- Related loop:
chr21:17675000-17700000~~chr21:18025000-18050000,
chr21:17925000-17950000~~chr21:18025000-18050000,
chr21:18025000-18050000~~chr21:18175000-18200000,
chr21:18025000-18050000~~chr21:18200000-18225000,
chr21:18025000-18050000~~chr21:18225000-18250000,
chr21:18025000-18050000~~chr21:18250000-18275000,
chr21:18025000-18050000~~chr21:18350000-18375000,
chr21:18040096-18042223~~chr21:18204238-18205925,
chr21:18040096-18042223~~chr21:18368086-18370037,
chr21:18040191-18042074~~chr21:18265543-18266810,
chr21:18040385-18042120~~chr21:18204504-18205995,
chr21:18040385-18042120~~chr21:18264749-18266732,
chr21:18040385-18042120~~chr21:18368469-18370118,
chr21:18040504-18041951~~chr21:18204494-18205803,
chr21:18040579-18041906~~chr21:18204448-18205978,
chr21:18040589-18041899~~chr21:18368433-18370077,
chr21:18040618-18041839~~chr21:18368630-18369881,