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Basic information

CohesinDB ID: CDBP00414108

Locus: chr21-18244362-18246003

Data sourse: ENCSR000BLD, GSE67783, GSE86191, GSE116868, ENCSR404BPV, GSE105028, GSE206145-NatGen2015, ENCSR000ECE, GSE206145, ENCSR198ZYJ, GSE38411

Cell type: RPE, H1-hESC, Fibroblast, HCT-116, MB157, Neurons-H1, BCBL-1, HSPC, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.900

Subunit: SA1,Rad21,SMC1,SA2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 31% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "13_ReprPC": 28%, "10_TssBiv": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, PGR, HMG20A, SOX2, XBP1, FOXA1, SUZ12, RING1B, ATF3, NFIC, CTCFL, CHD7, PRDM1, CBFB, MORC2, TP63, ZNF736, TEAD1, TRIM28, ELF1, ETV1, SNAI2, RBM39, RCOR2, ESR1, CTCF, TCF12, EP300, RYBP, E2F6, TRIM24, RAD51, SMC1, TEAD4, GATAD2A, EED, JARID2, NANOG, CHD8, BRD1, POU2F2, POU5F1, MYCN, TOP2A, KDM4C, BRD3, ZBTB17, ZBTB48, GATAD1, HNF4G, ERG, HOXC5, ASCL1, OGG1, MYC, SMARCA4, KDM4A, RAD21, GRHL3, PROX1, STAT3, XRCC5, PRDM14, NR2F6, NR3C1, KMT2A, CREB1, EZH2, GABPB1, PHF8, SPI1, HDAC2, ZNF644, MXD3, FLI1, MXI1, ETV5, RUNX1, SMC1A, EZH2phosphoT487, SIRT6, CRY1, ZNF335, ZFX, NFKBIA, SOX13, POU4F2, ZNF534, TET2, NMYC, TWIST1, RARA, ZNF701, BACH1, ZNF48, SMAD4, NCAPH2, MED1, ZEB1, TEAD3, KDM6B, L3MBTL2, SETDB1, BCL11A, HNF4A, ARID2, REST, ASH2L, HNRNPLL, CTBP2, BCOR, MBD2, FOXP1, AATF, SMC3, STAG1, TRP47, CBFA2T2, TBL1X, FOXA2, RBBP5, AGO1, MIER2, MAFF, CDK9, ZKSCAN1, KDM1A, YY1, RELA, NEUROD1, SP140, HIF1A, PCGF1, ZNF519, TAL1, MAX, MAF1, HAND2, TCF7L2, TP53, BRD2, AR, RXR, HEXIM1, TFIIIC, HSF1, RNF2, NOTCH3, BRD4, NCOR1, ZBTB26, AHR

Target gene symbol (double-evidenced CRMs): TMPRSS15

Function elements

Human SNPs: .

Number of somatic mutations (coding): 141

Number of somatic mutations (non-coding): 26

Related genes and loops

Related gene: ENSG00000154646,

eachgene

Deatailed information for cohesin site CDBP00414108