- Basic information
- CohesinDB ID: CDBP00414110
- Locus: chr21-18249657-18250255
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Data sourse: ENCSR000BLD, GSE72082, GSE126634, ENCSR000BLY, GSE105028, GSE111537, GSE25021, GSE108869, ENCSR000BTU, GSE143937, GSE115250, GSE138405, GSE152721, GSE145327, ENCSR000EEG, ENCSR000BLS, ENCSR000ECE, GSE97394, ENCSR000BTQ, ENCSR167MTG, ENCSR000EDE, GSE126990, GSE50893
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Cell type: MCF-7, H1-hESC, Hela-Kyoto, Hep-G2, Ishikawa, GM2588, HeLa-S3, HUES64, SK-N-SH, K-562, TC-32, OCI-AML-3, HAP1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 7% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
30% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 80%,
"14_ReprPCWk": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NKX2-2, POU5F1, SRF, CDK9, ERG, RELA, ZBTB2, NEUROD1, ONECUT1, MYC, SMARCA4, RAD21, HIF1A, OTX2, GABPA, STAT3, MAX, MED1, ARNTL, BCL11B, ZEB1, ESR1, SETDB1, CTCF, AR, IRF4, BRD4, TCF3, SMC1, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): TMPRSS15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 30
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154646,
- Related loop:
chr21:17350000-17375000~~chr21:18250000-18275000,
chr21:17650000-17675000~~chr21:18225000-18250000,
chr21:17650000-17675000~~chr21:18250000-18275000,
chr21:17675000-17700000~~chr21:18225000-18250000,
chr21:17825000-17850000~~chr21:18225000-18250000,
chr21:17850000-17875000~~chr21:18225000-18250000,
chr21:17925000-17950000~~chr21:18250000-18275000,
chr21:18000000-18025000~~chr21:18225000-18250000,
chr21:18025000-18050000~~chr21:18225000-18250000,
chr21:18025000-18050000~~chr21:18250000-18275000,
chr21:18050000-18075000~~chr21:18225000-18250000,
chr21:18100000-18125000~~chr21:18250000-18275000,
chr21:18225000-18250000~~chr21:18325000-18350000,
chr21:18225000-18250000~~chr21:18500000-18525000,
chr21:18250000-18275000~~chr21:25300000-25325000,