- Basic information
- CohesinDB ID: CDBP00414112
- Locus: chr21-18265848-18266487
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Data sourse: ENCSR230ZWH, GSE72082, GSE138405, GSE25021, ENCSR000BLY, ENCSR404BPV, GSE206145, GSE101921, GSE138105, GSE206145-NatGen2015, ENCSR000EDE, ENCSR198ZYJ, ENCSR000EHX, GSE103477, ENCSR703TNG, GSE126990, GSE108869, GSE94872, ENCSR917QNE
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Cell type: MCF-7, RPE, Hela-Kyoto, Fibroblast, MCF-10A, Neurons-H1, SLK, HUVEC, HeLa-S3, SK-N-SH, Liver, THP-1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 9% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.867
- Subunit: SMC3,Rad21,SA2,SA1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
28% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 95%,
"5_TxWk": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, TEAD1, PIAS1, RAD21, STAG1, ARNT, ESR1, BRD4, FOXA1, GABPA, SMC1, SMC3, CTCF, HOXB13, STAG2
- Target gene symbol (double-evidenced CRMs): TMPRSS15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 315
- Number of somatic mutations (non-coding): 45
- Related genes and loops