- Basic information
- CohesinDB ID: CDBP00414115
- Locus: chr21-18293535-18297034
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Data sourse: ENCSR230ZWH, ENCSR000FAD, ENCSR000BSB, ENCSR000EGW, GSE131606, ENCSR330ELC, ENCSR000BUC, ENCSR917QNE, GSE139435, GSE93080, GSE67783, GSE101921, ENCSR806UKK, GSE51234, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, ENCSR000EEG, ENCSR338DUC, ENCSR247LSH, GSE105004, ENCSR676MJK, GSE155324, ENCSR054FKH, ENCSR748MVX, ENCSR000ECS, GSE131577, ENCSR000BLD, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE106870, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR620NWG, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR760NPX, ENCSR000BLY, ENCSR150EFU, GSE121355, GSE111537, GSE25021, ENCSR000EAC, GSE122299, GSE115250, GSE76893, GSE145327, GSE76815, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, ENCSR217ELF, GSE131956, GSE110061, ENCSR000HPG, ENCSR335RKQ, ENCSR000EDE, GSE50893, GSE206145-GSE177045, GSE72082, ENCSR501LQA, ENCSR404BPV, GSE105028, ENCSR000EDW, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR807WAC, GSE62063, ENCSR495WGO, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR944ZCT, GSE126990
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Cell type: MDM, RH4, GM10847, GM2610, SLK, CVB-hiPSC, GM19240, HSPC, CVI-hiPSC, Liver, GP5d, TC-32, B-cell, H9-hESC, GM2630, RPE, Fibroblast, HEKn, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, GM18505, Leukemia-SEM, Lymphoblast, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, CNCCs-H9ESC, GM19193, HeLa-Tet-On, HAP1, THP-1, HUES64, MCF-7, GM12892, Ramos, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, MCF-10A, Neurons-H1, A-549, HUVEC, HCAEC, GM19238, HeLa, CNCC-WT33iPSC, OCI-AML-3, GM18951
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 61% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.300
- Subunit: NIPBL,SA1,Rad21,SMC1,SMC3ac,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
28% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 89%,
"14_ReprPCWk": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GATA2, FOXA2, GRHL3, FOXA1, SETDB1, GABPA, ERG
- Target gene symbol (double-evidenced CRMs): TMPRSS15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 144
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154646,
- Related loop:
chr21:17675000-17700000~~chr21:18275000-18300000,
chr21:17925000-17950000~~chr21:18275000-18300000,
chr21:18275000-18300000~~chr21:18375000-18400000,
chr21:18275000-18300000~~chr21:18450000-18475000,
chr21:18275000-18300000~~chr21:18475000-18500000,
chr21:18275000-18300000~~chr21:18500000-18525000,
chr21:18275000-18300000~~chr21:18725000-18750000,
chr21:18275000-18300000~~chr21:18775000-18800000,
chr21:18275000-18300000~~chr21:18800000-18825000,
chr21:18275000-18300000~~chr21:18900000-18925000,
chr21:18275000-18300000~~chr21:19325000-19350000,
chr21:18275000-18300000~~chr21:19500000-19525000,
chr21:18275000-18300000~~chr21:20025000-20050000,
chr21:18275000-18300000~~chr21:20425000-20450000,
chr21:18275000-18300000~~chr21:20550000-20575000,
chr21:18275000-18300000~~chr21:20875000-20900000,
chr21:18275000-18300000~~chr21:20950000-20975000,
chr21:18275000-18300000~~chr21:21200000-21225000,
chr21:18275000-18300000~~chr21:22775000-22800000,
chr21:18275000-18300000~~chr21:25025000-25050000,
chr21:18275000-18300000~~chr21:25375000-25400000,
chr21:18294262-18296416~~chr21:18368453-18369930,
chr21:18294283-18296358~~chr21:18368317-18370105,
chr21:18294478-18296370~~chr21:18368469-18370118,
chr21:18300000-18325000~~chr21:22775000-22800000,