- Basic information
- CohesinDB ID: CDBP00414129
- Locus: chr21-18368560-18369930
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE126634, GSE116868, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR000EDW, ENCSR917QNE, GSE115602, ENCSR000BTU, GSE93080, GSE115250, GSE138405, GSE76893, GSE101921, GSE152721, GSE206145-NatGen2015, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR703TNG, GSE116344, GSE138105, GSE145327, ENCSR000EEG, ENCSR000BLS, ENCSR000EHW, GSE85526, ENCSR000ECE, GSE206145, ENCSR000EHX, GSE97394, ENCSR000BTQ, GSE105004, GSE155324, ENCSR000EDE, GSE68388, GSE126990, GSE50893, ENCSR000ECS
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Cell type: MDM, RH4, GM2610, SLK, Liver, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, Fibroblast, HEKn, Ishikawa, HeLa-S3, H1-hESC, SNYDER, MB157, Lymphoblast, GM12878, GM2588, SK-N-SH, HeLa-Tet-On, THP-1, HUES64, MCF-7, Hela-Kyoto, MCF-10A, HEK293T, Hep-G2, Neurons-H1, A-549, HeLa, OCI-AML-3, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 23% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.611
- Subunit: SA1,Rad21,SMC3,SMC1,SA2,SMC3ac
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
28% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 87%,
"5_TxWk": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: USF1, GATA1, MYC, PBX4, XBP1, FOXA1, SPI1, USF2, CDK8, STAT3, MAX, GABPA, ZNF143, ZNF792, MITF, ERG
- Target gene symbol (double-evidenced CRMs): TMPRSS15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 20
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154646,
- Related loop:
chr21:17675000-17700000~~chr21:18350000-18375000,
chr21:17678473-17680046~~chr21:18368458-18370081,
chr21:17924283-17926719~~chr21:18368377-18371085,
chr21:17924291-17927223~~chr21:18368401-18369908,
chr21:17925000-17950000~~chr21:18350000-18375000,
chr21:18025000-18050000~~chr21:18350000-18375000,
chr21:18040096-18042223~~chr21:18368086-18370037,
chr21:18040385-18042120~~chr21:18368469-18370118,
chr21:18040589-18041899~~chr21:18368433-18370077,
chr21:18040618-18041839~~chr21:18368630-18369881,
chr21:18294262-18296416~~chr21:18368453-18369930,
chr21:18294283-18296358~~chr21:18368317-18370105,
chr21:18294478-18296370~~chr21:18368469-18370118,