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Basic information

CohesinDB ID: CDBP00414130

Locus: chr21-18370234-18370893

Data sourse: ENCSR000BLD, ENCSR404BPV, GSE105028, GSE152721, ENCSR000ECE, GSE206145-NatGen2015, GSE206145, ENCSR000EDE, ENCSR198ZYJ, GSE138105, GSE111537, GSE97394, GSE108869, ENCSR000ECS

Cell type: RPE, H1-hESC, Fibroblast, Neurons-H1, SLK, HeLa-S3, HUES64, OCI-AML-3, HAP1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 6% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.889

Subunit: SMC3,Rad21,SA2,SA1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 28% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 92%, "5_TxWk": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, NANOG, SMC1A, PGR, MEF2B, POU5F1, FOXA2, SOX2, GTF2B, SMAD3, MAFF, DUX4, FOXA1, SRF, CDK9, TRIM22, HOXB13, HOXC5, ZBTB2, MYC, ONECUT1, CTCFL, RAD21, PRDM1, HIF1A, OTX2, GABPA, STAT3, PAX5, TAL1, SMARCE1, CDK8, MED1, BACH2, SMAD1, STAG1, ESR1, CTCF, JUN, MAFK, SPI1, AR, REST, EGLN2, IRF4, FLI1, HSF1, BRD4, SMC1, SMC3, KMT2B, PDX1

Target gene symbol (double-evidenced CRMs): TMPRSS15

Function elements

Human SNPs: .

Number of somatic mutations (coding): 5

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154646,

eachgene

Deatailed information for cohesin site CDBP00414130