- Basic information
- CohesinDB ID: CDBP00414134
- Locus: chr21-18382887-18383716
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Data sourse: GSE206145, GSE206145-NatGen2015, GSE138105
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Cell type: RPE, SLK, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,SA1,Rad21,SA2,Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
28% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 89%,
"7_Enh": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MED1, RUNX1, FOSL1, NR3C1, YAP1, TEAD1, LHX2, GRHL3, BRD4, OTX2, SPI1, STAT3, TEAD4, JUN, MYF5, SMARCC1, MITF
- Target gene symbol (double-evidenced CRMs): TMPRSS15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 35
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154646,
- Related loop:
chr21:17650000-17675000~~chr21:18375000-18400000,
chr21:18275000-18300000~~chr21:18375000-18400000,
chr21:18375000-18400000~~chr21:18475000-18500000,
chr21:18375000-18400000~~chr21:18500000-18525000,
chr21:18375000-18400000~~chr21:18775000-18800000,
chr21:18375000-18400000~~chr21:18800000-18825000,
chr21:18375000-18400000~~chr21:18825000-18850000,
chr21:18375000-18400000~~chr21:18900000-18925000,
chr21:18375000-18400000~~chr21:19025000-19050000,
chr21:18375000-18400000~~chr21:20875000-20900000,
chr21:18387505-18389165~~chr21:18498641-18500962,