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Basic information

CohesinDB ID: CDBP00414135

Locus: chr21-18384631-18385295

Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, GSE126634, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR917QNE, ENCSR000BTU, GSE143937, ENCSR000BKV, GSE115250, GSE138405, GSE76893, GSE152721, GSE206145-NatGen2015, ENCSR198ZYJ, GSE112028, GSE130135, GSE138105, GSE145327, GSE94872, ENCSR000BLS, GSE206145, ENCSR000ECE, GSE62063, ENCSR000EHX, GSE97394, GSE105004, GSE110061, GSE129526, ENCSR000EDE, GSE126990, ENCSR000ECS, GSE131577

Cell type: MDM, SLK, Liver, TC-32, H9-hESC, RPE, Fibroblast, Ishikawa, HeLa-S3, K-562, H1-hESC, SK-N-SH, HeLa-Tet-On, THP-1, HUES64, MCF-7, Ramos, Hela-Kyoto, HCT-116, HL-60, HEK293T, Hep-G2, Neurons-H1, A-549, HUVEC, HeLa, OCI-AML-3, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 18% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.689

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 28% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 96%, "9_Het": 2%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: SMC1A, NKX2-2, CDK7, SMAD3, STAT1, SRF, MEF2C, CDK9, HOXB13, YY1, CTCFL, RAD21, STAT3, MAFB, NKX3-1, ZNF143, MED1, STAT5B, CREB1, STAG1, ESR1, SETDB1, CTCF, JUN, NR4A1, IRF4, HSF1, BRD4, SMC1, SMC3, STAG2, AHR

Target gene symbol (double-evidenced CRMs): TMPRSS15

Function elements

Human SNPs: .

Number of somatic mutations (coding): 6

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154646,

eachgene

Deatailed information for cohesin site CDBP00414135